Results 181 to 190 of about 180,512 (273)
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley +1 more source
The antiarrhythmic effects of the nucleoside transporter inhibitor, R75231, in anaesthetized pigs [PDF]
Cherry L. Wainwright+2 more
openalex +1 more source
ABSTRACT Background In radiotherapy for early‐stage glottic cancer, evaluating the target surface dose at the glottic air–tissue boundary is crucial, as buildup effect can cause underdosing. The accuracy of dose evaluation in the surrounding tissues is affected by both the dose calculation algorithms and the accuracy of the Hounsfield unit values in ...
Yuki Saito+3 more
wiley +1 more source
Abstract Purpose This study compares the dosimetric accuracy of deep‐learning‐based MR synthetic CT (sCT) in brain radiotherapy between the Analytical Anisotropic Algorithm (AAA) and AcurosXB (AXB). Additionally, it proposes a novel metric to predict the dosimetric accuracy of sCT for individual post‐surgical brain cases.
Jeffrey C. F. Lui+3 more
wiley +1 more source
A Python package for fast GPU‐based proton pencil beam dose calculation
Abstract Purpose Open‐source GPU‐based Monte Carlo (MC) proton dose calculation algorithms provide high speed and unparalleled accuracy but can be complex to integrate with new applications and remain slower than GPU‐based pencil beam (PB) methods, which sacrifice some physical accuracy for sub‐second plan calculation.
Mahasweta Bhattacharya+4 more
wiley +1 more source
Localization of neuronal and glial glutamate transporters
Jeffrey D. Rothstein+7 more
openalex +1 more source
Abstract Purpose An evaluation of the accuracy, safety, and efficiency of the Halcyon ring delivery system (RDS) for stereotactic radiosurgery (SRS) treatment to relatively small (1–3 cm) brain lesions. Methods After completing the extensive in‐house quality assurance checks including Winston–Lutz test and independent dose verification via MD Anderson ...
Kate Hazelwood+5 more
wiley +1 more source