Results 181 to 190 of about 180,512 (273)

Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review

open access: yesAging and Cancer, EarlyView.
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley   +1 more source

Transportes

open access: yesBrasil em números, 2020
openaire   +1 more source

Evaluation of the glottic surface dose in three‐dimensional conformal radiotherapy for early‐stage glottic cancer using a treatment planning system

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
ABSTRACT Background In radiotherapy for early‐stage glottic cancer, evaluating the target surface dose at the glottic air–tissue boundary is crucial, as buildup effect can cause underdosing. The accuracy of dose evaluation in the surrounding tissues is affected by both the dose calculation algorithms and the accuracy of the Hounsfield unit values in ...
Yuki Saito   +3 more
wiley   +1 more source

Does dose calculation algorithm affect the dosimetric accuracy of synthetic CT for MR‐only radiotherapy planning in brain tumors?

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose This study compares the dosimetric accuracy of deep‐learning‐based MR synthetic CT (sCT) in brain radiotherapy between the Analytical Anisotropic Algorithm (AAA) and AcurosXB (AXB). Additionally, it proposes a novel metric to predict the dosimetric accuracy of sCT for individual post‐surgical brain cases.
Jeffrey C. F. Lui   +3 more
wiley   +1 more source

A Python package for fast GPU‐based proton pencil beam dose calculation

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Open‐source GPU‐based Monte Carlo (MC) proton dose calculation algorithms provide high speed and unparalleled accuracy but can be complex to integrate with new applications and remain slower than GPU‐based pencil beam (PB) methods, which sacrifice some physical accuracy for sub‐second plan calculation.
Mahasweta Bhattacharya   +4 more
wiley   +1 more source

Localization of neuronal and glial glutamate transporters

open access: hybrid, 1994
Jeffrey D. Rothstein   +7 more
openalex   +1 more source

An investigation into the feasibility and efficacy of stereotactic radiosurgery for 1–3 cm single brain lesions on the ring‐mounted Halcyon LINAC

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose An evaluation of the accuracy, safety, and efficiency of the Halcyon ring delivery system (RDS) for stereotactic radiosurgery (SRS) treatment to relatively small (1–3 cm) brain lesions. Methods After completing the extensive in‐house quality assurance checks including Winston–Lutz test and independent dose verification via MD Anderson ...
Kate Hazelwood   +5 more
wiley   +1 more source

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