Results 71 to 80 of about 636,269 (313)

Response and Tolerance of Macleaya cordata to Excess Zinc Based on Transcriptome and Proteome Patterns

open access: yesPlants, 2023
Macleaya cordata is a dominant plant of mine tailings and a zinc (Zn) accumulator with high Zn tolerance. In this study, M. cordata seedlings cultured in Hoagland solution were treated with 200 μmol·L−1 of Zn for 1 day or 7 days, and then, their leaves ...
Hongxiao Zhang   +6 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

To Transport or Not to Transport: Post‐Growth Avenues for Transport Infrastructure Planning

open access: yesJournal of Critical Infrastructure Policy
AbstractPost‐growth literature has recently raised attention to the role of transport infrastructure planning in relation to global sustainability challenges and human wellbeing. Transport infrastructure can be a major obstacle to change, due to sunk costs, material intensity, and historical path dependencies.
Stefan Verweij   +2 more
openaire   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

AIR TRANSPORTS – COMPONENT OF INTERNATIONAL TRANSPORTS [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2009
Air transports activity has known an important development caused by the economic increase, by Romania’s involvement in the international products trade, in international tourism. They are completed by the specific characteristics of air transports, which, together with the characteristics of the other ways of transport, has certain transport ...
Mihaela Loredana LAPADUSI   +1 more
openaire   +2 more sources

The NorM MATE transporter from N. gonorrhoeae: insights into drug and ion Binding from atomistic molecular dynamics simulations [PDF]

open access: yes, 2014
The multidrug and toxic compound extrusion transporters extrude a wide variety of substrates out of both mammalian and bacterial cells via the electrochemical gradient of protons and cations across the membrane.
Khalid, Syma   +7 more
core   +1 more source

Prescription Advice Based on Data of Drug-Drug-Gene Interaction of Patients with Polypharmacy

open access: yesPharmacogenomics and Personalized Medicine, 2022
Sandro Salamone,1 Sara Spirito,2 Maurizio Simmaco,2 Marius Unger,1 Saskia Preissner,3 Björn-Oliver Gohlke,1 Andreas Eckert,1 Robert Preissner1 1Science-IT and Institute of Physiology, Charité – Universitätsmedizin Berlin, Corporate Member of Freie ...
Salamone S   +7 more
doaj  

Molecular Characteristics of the Conserved Aspergillus nidulans Transcription Factor Mac1 and Its Functions in Response to Copper Starvation

open access: yesmSphere, 2019
Copper (Cu) is an essential trace element in all organisms, and Cu acquisition during periods of starvation is important for cell survival and proliferation.
Zhendong Cai   +4 more
doaj   +1 more source

Advances in Understanding Silicon Transporters and the Benefits to Silicon-Associated Disease Resistance in Plants

open access: yesApplied Sciences, 2022
Silicon (Si) is the second most abundant element after oxygen in the earth’s crust and soil. It is available for plant growth and development, and it is considered as quasi-essential for plant growth.
Ruonan Li   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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