Results 91 to 100 of about 32,498 (309)

Logística de transportes: estudo da importância do serviço de encomendas da Auto Viação Catarinense [PDF]

open access: yes, 2009
TCC (graduação) - Universidade Federal de Santa Catarina, Centro Sócio Economico, Curso de Administração.O presente trabalho foi desenvolvido com a finalidade de verificar a importância da logística do transporte de encomendas em ônibus de passageiros ...
Turnes, Nicolli Carla Back
core  

Cruzar a metrópole

open access: yesPlural, 2018
Inserido nos debates sobre a mobilidade, esse artigo discute o papel dos transportes coletivos na vida urbana, com uma análise específica do município de Ribeirão das Neves, localizado na Região Metropolitana de Belo Horizonte. Partindo do pressuposto de
Marina Abreu Torres
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Panorama da infraestrutura de transportes no país após a pandemia

open access: yes, 2020
A pandemia já causou transformações drásticas. Uma delas foi a redução de 40% do transporte de cargas no país, deixando 75% das empresas de transporte operando no vermelho, o que pode atrasar o programa de investimentos do governo federal. Quem fala mais
Quintella, Marcus
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Routes of public transport and the situation of tuberculosis in Lima, Peru

open access: yesRevista Peruana de Medicina Experimental y Salud Pública, 2015
In order to determine the association between the number of formal urban public transport routes and the situation of tuberculosis (TB) in each district of Lima, a correlational analysis and linear regression model between the two variables was performed.
Octavio Garaycochea, Eduardo Ticona
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

Andante

open access: yes, 2015
O Andante é o nome dos bilhetes utilizados nos transportes área metropolitana do Porto.
TIP-Transportes Intermodais do Porto
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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