Results 31 to 40 of about 3,135 (212)

To Transport or Not to Transport: Post‐Growth Avenues for Transport Infrastructure Planning

open access: yesJournal of Critical Infrastructure Policy
AbstractPost‐growth literature has recently raised attention to the role of transport infrastructure planning in relation to global sustainability challenges and human wellbeing. Transport infrastructure can be a major obstacle to change, due to sunk costs, material intensity, and historical path dependencies.
Stefan Verweij   +2 more
openaire   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

UMA CONTRIBUIÇÃO À SOLUÇÃO DO PROBLEMA DE ROTEAMENTO COM MÚLTIPLOS OBJETIVOS

open access: yesTransportes, 1995
Este trabalho foi desenvolvido a fim de apresentar soluções para o problema de roteamento com múltiplos objetivos. No intuito de analisar a solução para este tipo de problema foi estudado o caso de sistema de ônibus fretado.
André Tadeu Paes de Souza   +1 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Entre o conservadorismo orçamentário e o desenvolvimento regional. Finanças públicas e infraestrutura de transportes em Minas Gerais na Primeira República

open access: yesAmérica Latina en la Historia Económica, 2017
O principal escopo é examinar, com base em novas evidências, a evolução das finanças públicas de Minas Gerais na República Velha, com destaque para o lugar do dispêndio com a infraestrutura de transportes.
Marcelo Godoy   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Turismo de eventos: los cruceros españoles en la inauguración del Canal de Suez de 1869

open access: yesCuadernos de Turismo, 2015
El 17 de noviembre de 1869 tuvo lugar el solemne acto de inauguración del Canal de Suez. Largamente celebrado por los medios de información, el histórico acontecimiento atrajo visitantes de toda Europa, generando asimismo la promoción de varios viajes ...
Gaetano Cerchiello
doaj   +1 more source

The transport disadvantaged — community transport or mainstream? [PDF]

open access: yesTransportation Planning and Technology, 1995
This paper is based on a study undertaken for the New South Wales Department of Transport in 1991 to examine the cost of providing transport services for the aged and those with disabilities through the Community Transport program. A sample of Community Transport Projects in N.S.W. country and metropolitan areas was studied in detail and data collected
Battellino, Helen C., Hensher, David A.
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Preparation of a Smart Port Indicator and Calculation of a Ranking for the Spanish Port System

open access: yesLogistics, 2020
Nowadays, the denomination of “smart” is associated with several production and management devices and to logistics and distribution, too. Thus, this qualification is used in different application fields.
Alberto Rodrigo González   +3 more
doaj   +1 more source

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