Results 41 to 50 of about 3,135 (212)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Metropolitan dynamics and mobility times. Metropolitan region of Barcelona as example
Metropolitan areas have been studies from the perspective of the spatial relationships mapped out by work commutes. This article attempts to complement this single-function view of reality of metropolitan life by presenting everyday journeys as ...
Carme Miralles-Guasch
doaj +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Este artigo analisa o comportamento das exportações como função da disponibilidade da infraestrutura de transporte e do nível de PIB per capita das microrregiões brasileiras em 2003.
Admir Antonio Betarelli Junior +1 more
doaj +1 more source
Liderança relacional em rede do setor de transportes brasileiro
A gestão de uma empresa organizada em rede amplia a construção de relacionamentos que fortalecem a cooperação e a otimização de recursos para além do plano líder-liderado, requerendo articulação e cooperação entre os níveis individuais, organizacionais e
Éderson Tomasi da Silva +2 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Propuestas para reducir el contagio de tuberculosis en el transporte público
La tuberculosis es una enfermedad de reconocida importancia en el mundo. Perú posee la incidencia más alta de la región andina con 38 000 casos nuevos durante 2013.1 El 57% de casos se ubica en Lima y Callao…
Sergio Hervias-Marquina +1 more
doaj +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source

