Results 131 to 140 of about 71,276 (310)

A Proof‐of‐Concept Assessment of a Novel Wearable Eyelid Muscle Device: A Pre‐Clinical Animal Cadaver Study for Eyelid Closure Restoration

open access: yesAdvanced Robotics Research, EarlyView.
This article introduces a soft wearable eyelid sling device incorporating a hydraulic soft artificial muscle (SAM) for achieving complete closure of an eyelid. The SAM is driven by a cam mechanism that provides a displacement profile closely matched with those of a healthy eyelid.
Patrick Pruscino   +7 more
wiley   +1 more source

Transposable elements and viruses as factors in adaptation and evolution: an expansion and strengthening of the TE-Thrust hypothesis

open access: yes, 2012
In addition to the strong divergent evolution and significant and episodic evolutionary transitions and speciation we previously attributed to TE-Thrust, we have expanded the hypothesis to more fully account for the contribution of viruses to TE-Thrust ...
Oliver, K.R., Greene, W.K.
core  

Gait Analysis of Pak Biawak: A Necrobot Lizard Built using the Skeleton of an Asian Water Monitor (Varanus Salvator)

open access: yesAdvanced Robotics Research, EarlyView.
Pak Biawak, a necrobot, embodies an unusual fusion of biology and robotics. Designed to repurpose natural structures after death, it challenges conventional boundaries between nature and engineering. Its movements are precise yet unsettling, raising questions about sustainability, ethics, and the untapped potential of biointegrated machines.
Leo Foulds   +2 more
wiley   +1 more source

Backpropagation Through Soft Body: Investigating Information Processing in Brain–Body Coupling Systems

open access: yesAdvanced Robotics Research, EarlyView.
This study explores how information processing is distributed between brains and bodies through a codesign approach. Using the “backpropagation through soft body” framework, brain–body coupling agents are developed and analyzed across several tasks in which output is generated through the agents’ physical dynamics.
Hiroki Tomioka   +3 more
wiley   +1 more source

Pathogenic tau-induced piRNA depletion promotes neuronal death through transposable element dysregulation in neurodegenerative tauopathies

open access: yes, 2018
Transposable elements, known colloquially as 'jumping genes', constitute approximately 45% of the human genome. Cells utilize epigenetic defenses to limit transposable element jumping, including formation of silencing heterochromatin and ...
Frost, Bess   +9 more
core   +1 more source

Efficient and Robust Standing Postures of Quadruped Robots

open access: yesAdvanced Robotics Research, EarlyView.
A calibrated static framework estimates load, optimizes torques, and adapts posture so quadruped robots stand efficiently and robustly under external payloads, achieving up to 50% lower torque demand. Inspired by the natural posture adjustments of animals under external loading, this article presents an optimization‐based framework for minimizing joint
Mohamad Kanaan   +5 more
wiley   +1 more source

Parental genetic distance and transposable element load influence transposable element dynamics in young Nicotiana allotetraploids

open access: yes, 2019
International audienceAs postulated by Barbara McClintock, allopolyploidy (interspecific hybridization associated with genome duplication) would represent a genomic shock, involving genome changes driven by transposable elements.
Lim, K, Y   +8 more
core  

Mesenchymal Stromal Cell‐Mediated Intercellular Communication: Mapping the Interactome for Skeletal Muscle Homeostasis and Regeneration

open access: yesAdvanced Science, EarlyView.
Liu et al. define a systems‐level interactome of fibroadipogenic progenitor (FAP)‐mediated signaling in skeletal muscle by integrating single‐cell transcriptomics with FAP depletion‐based perturbation analysis. Functional interrogation using a conditioned media bioassay links predicted signaling to multicellular outcomes, establishing a framework to ...
Xingyu Liu   +13 more
wiley   +1 more source

Regulation of maize Ac/Ds transposition by replication and DNA methylation [PDF]

open access: yes, 2001
In maize the transposable elements Activator/Dissociation (Ac/Ds) transpose shortly after replication from one of the two resulting chromatids ("chromatid selectivity"). A model was suggested that explains this phenomenon as a consequence of different Ac
Ros, Francesca
core  

Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome

open access: yesAdvanced Science, EarlyView.
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu   +19 more
wiley   +1 more source

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