Results 231 to 240 of about 1,813,007 (299)

TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis

open access: yesAdvanced Science, EarlyView.
A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu   +12 more
wiley   +1 more source

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

open access: yesAdvanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou   +9 more
wiley   +1 more source

Comparative Analysis of Transposable Element Evolution in Crustaceans. [PDF]

open access: yesGenome Biol Evol
Zeng X   +7 more
europepmc   +1 more source

Transposable element-mediated DNA methylation of the NAC20 and NAC26 promoters led to a maternal effect on grain filling. [PDF]

open access: yesJ Integr Plant Biol
Wu MW   +9 more
europepmc   +1 more source

<i>Cis</i>-regulatory effects of transposable element insertion/absence polymorphisms in the <i>Brassica napus</i> population. [PDF]

open access: yesHortic Res
Yuan G   +12 more
europepmc   +1 more source

Targeting MORC2 activates transposable element-mediated viral mimicry and potentiates immune checkpoint blockade in triple-negative breast cancer. [PDF]

open access: yesMol Cancer
Zhang FL   +11 more
europepmc   +1 more source

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