Results 231 to 240 of about 71,276 (310)

CHCHD10 Mitigates Alzheimer's Disease‐Related Phenotypes in Association With Epigenetic Remodeling in Directly Reprogrammed Neurons

Advanced Science, EarlyView.
CHCHD10 loss in Alzheimer's disease is associated with mitochondrial dysfunction, epigenomic disruption, and tau pathology. Restoration of CHCHD10 shifts DNA methylation toward a non‐disease state and reduces tau and amyloid pathology, with KATNAL2 acting as a downstream effector.
Teresa M. Thomas, Ching‐Yao Yang, Kexin Zhang, Liam Wetzel, Dina Bugybayeva, Julia Ferguson, Md Mahmudul Hasan, William Samsa, Nandita Patil, Anshul Dash, Tarini Gowda, Xiongwei Zhu, Feixiong Cheng, Tian Liu   +13 more
wiley   +1 more source

Transposable Element-Derived miR-28-5p and miR-708-5p: Exploring Potential Roles in Lung Cancer. [PDF]

Noncoding RNA
Chira S, Braicu C, Strilciuc S, Calin GA, Berindan-Neagoe I.   +4 more
europepmc   +1 more source

Wearable‐Derived Diurnal Alignment Between Physical Activity and Device Temperature Predicts Future Disease and Mortality Risk

Advanced Science, EarlyView.
Wearable‐derived diurnal alignment between physical activity and device temperature, decomposed into 24 h coupling strength (M24), phase deviation (D24), and 12 h harmonic magnitude (M12), is examined in approximately 90,000 UK Biobank participants.
Han Chen, Jiahe Wei, Jonathan Cedernaes, Christian Benedict, Athanasios Tsanas, Zhi Cao, Xiao Tan   +6 more
wiley   +1 more source

TE-SCALE: a comprehensive database for exploring transposable element expression across human cancers at single-cell resolution. [PDF]

Nucleic Acids Res
Meng X, Nie Z, Wang Q, Hu Y, Deng Y, Ai N, Huang Z, Li Y, Yuan Y, Xiao J, Zeng J, Li G, Jiang L.   +12 more
europepmc   +1 more source

Correcting Apparent Priming Bias Unveils Fertilizer Nitrogen‐Risk Archetypes of Surplus and Depletion Across Asian Rice Systems

Advanced Science, EarlyView.
Correcting the apparent priming effect resolves systematic biases in Asian rice fertilizer nitrogen accounting. Net soil retention drops below 7%, while 48% of fertilizer escapes, inflicting US$98.53 billion in annual reactive‐nitrogen damages. High‐resolution mapping uncovers N‐risk archetypes across 42% of the rice area, delivering a spatially ...
Xiuyun Liu, Siyuan Cai, Longlong Xia, Jagdish K. Ladha, Xiaoyuan Yan, Xu Zhao   +5 more
wiley   +1 more source

Transposable element expression is associated with sex chromosome number in humans. [PDF]

PLoS Genet
Teoli J, Merenciano M, Fablet M, Necsulea A, Siqueira-de-Oliveira D, Brandulas-Cammarata A, Labalme A, Lejeune H, Lemaitre JF, Gueyffier F, Sanlaville D, Bardel C, Vieira C, Marais GA, Plotton I.   +14 more
europepmc   +1 more source

Nano‐Backpack Engineered Probiotics with Reactive Oxygen Species–Responsive Tungsten Release for Synergistic Therapy of Inflammatory Bowel Disease

Advanced Science, EarlyView.
An integrated probiotic system is engineered to execute a programmed therapeutic cascade against inflammatory bowel disease. Upon pathological signals, the system sequentially performs ROS scavenging, tungsten release, and selective pathogen suppression, thereby breaking the oxidative stress–dysbiosis cycle to remodel gut microbiota and reinforce ...
Yang Yang, Liucan Wang, Guoqing Chen, Yuanling Zhang, Jiarui Shi, Wenzhe Fan, Min Yu, Jixi Zhang, Hua Yang   +8 more
wiley   +1 more source

Gene and transposable element expression in response to stress in temperate and tropical populations of Drosophila. [PDF]

Mob DNA
Merenciano M, Oliveira DS, Salces-Ortiz J, Rebollo R, Manfré B, Menezes B, Krasovec G, Simonet C, Janillon S, Burlet N, Carareto CMA, Vieira C, Fablet M.   +12 more
europepmc   +1 more source

Machine‐Learning Framework for Designing Stable Interfaces in All‐Solid‐State Lithium‐Ion Batteries

Advanced Science, EarlyView.
A data‐driven strategy is developed to discover coating materials for all‐solid‐state lithium batteries. Using calculations of interfacial reactivity, unsupervised pattern recognition, and machine‐learning prediction, the study identifies low‐reactivity compositional patterns and screens new lithium‐based oxide and polyanion candidates, extending ...
Sehyeok Park, Myeongcho Jang, Hun‐Gi Jung, Kyung Yoon Chung, Seungho Yu   +4 more
wiley   +1 more source

The poplar pathogen <i>Sphaerulina musiva</i> has a dynamic genome architecture marked by chromosomal inversions and changes in transposable element abundance. [PDF]

Microb Genom
Zaccaron AZ, Lassagne A, Søndreli KL, Sudermann MA, Alcalá Briseño RI, Grünwald NJ, Weisberg AJ, LeBoldus JM.   +7 more
europepmc   +1 more source