Results 231 to 240 of about 102,438 (334)
Using field‐based holo‐omics, we demonstrate that developmental shifts in sorghum leaf metabolomes drive a noncanonical fungal succession from stress tolerators (S) through ruderals (R) to competitors (C). Antifungal metabolites in young leaves select for S strategists with expanded genomes, transient maltose pulses during flowering favor fast‐growing ...
Peilin Chen, John W. Taylor, Cheng Gao
wiley +1 more source
Transposable Element-Derived miR-28-5p and miR-708-5p: Exploring Potential Roles in Lung Cancer. [PDF]
Chira S +4 more
europepmc +1 more source
Distinct Biotypes of Visual Perception in Major Depressive Disorder
In a discover dataset (272 acute MDD patients), this work identifies a novel depression biotype characterized by impaired visual motion perception, using machine learning clustering. An independent dataset confirms the robustness of this biotype through cross‐validation and demonstrates its generalizability.
Zhuoran Cai +13 more
wiley +1 more source
Gene and transposable element expression in response to stress in temperate and tropical populations of Drosophila. [PDF]
Merenciano M +12 more
europepmc +1 more source
The Landscape and Regulation of Histone Crotonylation in Mammalian Gametes and Early Embryos
Histone crotonylation undergoes a genome‐wide transition from broad domains to canonical narrow peaks during minor zygotic genome activation (ZGA). This remodeling is required for proper major ZGA and blastocyst formation. Disruption of this transition by transcriptional inhibition, metabolic perturbation, or HDAC1 dysfunction impairs embryonic ...
Shenli Yuan +8 more
wiley +1 more source
Transposable element expression is associated with sex chromosome number in humans. [PDF]
Teoli J +14 more
europepmc +1 more source
This study reveals a citrate–ACLY–H3K27ac metabolic–epigenetic axis driving inflammatory gene activation and kidney fibrosis, highlighting ACLY inhibition as a potential therapeutic strategy for chronic kidney disease (CKD). ABSTRACT The mechanisms by which metabolic stress drives epigenetic dysregulation and fibrosis in chronic kidney disease (CKD ...
Chunxiu Du +15 more
wiley +1 more source

