TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis
A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu +12 more
wiley +1 more source
The jujube pan-TE map identifies transposable element insertions associated with domestication and pericarp development. [PDF]
Li X +7 more
europepmc +1 more source
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou +9 more
wiley +1 more source
Comparative Analysis of Transposable Element Evolution in Crustaceans. [PDF]
Zeng X +7 more
europepmc +1 more source
scTELL: a single-cell ATAC-seq tool for locus-specific transposable element identification in chromatin accessibility. [PDF]
Jeong K, Ha H, Xing J, Choi J, Kim K.
europepmc +1 more source
Transposable element-mediated DNA methylation of the NAC20 and NAC26 promoters led to a maternal effect on grain filling. [PDF]
Wu MW +9 more
europepmc +1 more source
<i>Cis</i>-regulatory effects of transposable element insertion/absence polymorphisms in the <i>Brassica napus</i> population. [PDF]
Yuan G +12 more
europepmc +1 more source
Targeting MORC2 activates transposable element-mediated viral mimicry and potentiates immune checkpoint blockade in triple-negative breast cancer. [PDF]
Zhang FL +11 more
europepmc +1 more source
A comparative analysis of transposable element diversity and evolution across 75 bee genomes. [PDF]
Cook HL +3 more
europepmc +1 more source

