Results 141 to 150 of about 112,710 (289)

Epigenetic Deregulation of Transposable Elements Links Developmental Processes and Tumorigenesis. [PDF]

Int J Mol Sci
Lynch-Sutherland C, Stockwell P, Chatterjee A, Eccles MR, Macaulay E.   +4 more
europepmc   +1 more source

Transposable element in fish [PDF]

Nature, 1996
A, Koga, M, Suzuki, H, Inagaki, Y, Bessho, H, Hori   +4 more
openaire   +2 more sources

Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time‐Restricted Feeding Protection in Crohn's Disease

Advanced Science, EarlyView.
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang, Huishi Tan, Senhui Weng, Yuntao Liu, Lingxu Song, Shaoyu Cheng, Zelong Lin, Jiawei Chen, Fei Tan, Jun Wang, Jinke Huang, Linkun Cai, Jiwei Chai, Cailing Zhong, Yanqiang Shi, Wendi Zhang, Haiyan Zhang, Chongyang Huang   +17 more
wiley   +1 more source

Transposable elements hitchhike on Starships across fungal genomes. [PDF]

Nat Commun
Griem-Krey H, de Fraga Sant'Ana J, Oggenfuss U, Calegari-Alves YP, Marques AL, Berger M, Santi L, Beys-da-Silva WO, Habig M.   +8 more
europepmc   +1 more source

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

Advanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang, Ya‐Ning Wang, Da Lin, Jia‐Yang Xu, Feng‐Yuan Qi, Hui‐Ling Cui, Hui‐Jie Lu, Min Qiao, Edward Topp, Dong Zhu, Matthias C. Rillig, Yong‐Guan Zhu   +11 more
wiley   +1 more source

Dissecting the contribution of transposable elements to interphase chromosome structure. [PDF]

Genome Biol
Shi L, Xiao Z, Zhou X, Babarinde IA, Fu X, Ma G, Huang Z, Sun L, He J, Strunnikov A, Hutchins AP.   +10 more
europepmc   +1 more source

Bioenergy Cropping Reduces the Spatiotemporal Scaling of Soil Bacterial Biodiversity

Advanced Science, EarlyView.
Consistent with patterns observed in plant and animal communities, soil bacterial communities exhibit significant species–time–area and phylogenetic–time–area relationships independent of nested structure. Bioenergy cropping significantly reduces the spatiotemporal scaling rates, particularly in sandy loam soils.
Zhencheng Ye, Jialiang Kuang, Colin T. Bates, Arthur Escalas, Daliang Ning, Liyou Wu, Suo Liu, Sihang Deng, Jiesi Lei, Xiangwen Chen, Jennifer Pett‐Ridge, Malay Saha, Lauren Hale, Gangsheng Wang, Renmao Tian, Ying Fu, Yu Tang, Mary Firestone, Jizhong Zhou, Yunfeng Yang   +19 more
wiley   +1 more source

Structural heterogeneity and functional convergence of transposable elements. [PDF]

Front Genet
Kosovsky GY, Glazko GV, Glazko TT.
europepmc   +1 more source

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu, Shizhen Qiu, Zhitong Wang, Dan Li, Min Chen, Yinying Chu, Guangfei Li, Yi Fang, Changjiang Li, Fang Shi, Peijie He, Haitao Wu, Haopeng Wang, Jian Chen   +13 more
wiley   +1 more source

Derepression of transposable elements in the mouse prefrontal cortex disrupts social behavior. [PDF]

Proc Natl Acad Sci U S A
Kim RK, Smith C, Truby NL, Strandberg SR, Bell JL, Carwile N, Silva GM, Neve RL, Aung T, Cui X, Hamilton PJ.   +10 more
europepmc   +1 more source