Results 161 to 170 of about 65,487 (217)

scResponse: A Rank‐Based Method for Identifying Cell States That Contribute to Immunotherapy Response by Single‐Cell Data

Advanced Science, EarlyView.
Although the tumor microenvironment is known to shape immunotherapy response, its key determinants remain elusive, underscoring the critical need for single‐cell resolution analytical frameworks. We present scResponse, an efficient algorithm to quantify single‐cell responses to immunotherapy. By capturing diverse cellular subtypes and states associated
Qi Dong, Haijun Huang, Yuxiu Wang, Bo Jiang, Yuzheng Chen, Huanhuan Xu, Jing Ren, Shengnan Guo, Tianhao Li, Mingjie Zhang, Tianyu Zhai, Wenbo Yang, Kaidong Liu, Cheng Lyu, Jingxuan Kang, Mingshuo Zhang, Yupeng Lu, Binghui Si, Shujun Cao, Dandan Xu, Zong Chen, Dapeng Hao   +21 more
wiley   +1 more source

Sex-biased Expression of Genes and Transposable Elements in Hybrids from Drosophila mojavensis and Drosophila arizonae. [PDF]

Genome Biol Evol
Simão MC, Oliveira DS, Nunes WVB, Banho CA, Ferrarini MG, Carareto CMA, Vieira C.   +6 more
europepmc   +1 more source

Multi‐Tissue Omics Analysis Uncovers Translational Regulation Underlying Complex Traits in Pigs

Advanced Science, EarlyView.
Integrated multi‐omics across pig breeds and tissues reveals key principles of post‐transcriptional translational regulation and their contribution to trait formation. A gene network framework integrating transcriptomic and translatomic data is developed and applied to elucidate the genetic basis of meat production, offering new insights into mammalian
Chao Wang, Yuanyuan Zhang, Choulin Chen, Xiaoxian Xu, Shenghua Qin, Junyan Qi, Yongzhou Bao, Huiming Li, Ruipu Chen, Weigang Zheng, Zhilong Chen, Lingzhao Fang, Yunxiang Zhao, Yuwen Liu   +13 more
wiley   +1 more source

Molecular Mimicry of Transposable Elements in Plants. [PDF]

Plant Cell Physiol
Chu J, Newman J, Cho J.
europepmc   +1 more source

Model‐Inversion‐Resistant Physical Unclonable Neural Network Using Vertical NAND Flash Memory

Advanced Science, EarlyView.
Schematic and key features of the proposed forward‐forward physical unclonable neural network (FF‐PUNN), incorporating a concealable physical unclonable function (PUF) layer and forward‐forward (FF) learning. ABSTRACT The growing use of neural networks in privacy‐sensitive applications necessitates architectures that inherently protect both data and ...
Sung‐Ho Park, Ryun‐Han Koo, Jonghyun Ko, Jiseong Im, Yeongheon Yang, Mingyun Oh, Dongbeen Shin, Gyuweon Jung, Jong‐Ho Lee   +8 more
wiley   +1 more source

Transposable elements in health and disease: Molecular basis and clinical implications. [PDF]

Chin Med J (Engl)
Hong Y, Liu N.
europepmc   +1 more source

Linking Plant Metabolomics with Fungal Functional Dynamics Reveals a Noncanonical S‐R‐C Adaptive Trajectory

Advanced Science, EarlyView.
Using field‐based holo‐omics, we demonstrate that developmental shifts in sorghum leaf metabolomes drive a noncanonical fungal succession from stress tolerators (S) through ruderals (R) to competitors (C). Antifungal metabolites in young leaves select for S strategists with expanded genomes, transient maltose pulses during flowering favor fast‐growing ...
Peilin Chen, John W. Taylor, Cheng Gao
wiley   +1 more source

Identification of transposable elements and satellite DNA in the Neotropical species Drosophila amaguana from the Ecuadorian Andean Forests. [PDF]

PLoS One
Coba-Males MA, Orozco-Arias S, Guyot R, Vela D.   +3 more
europepmc   +1 more source

Distinct Biotypes of Visual Perception in Major Depressive Disorder

Advanced Science, EarlyView.
In a discover dataset (272 acute MDD patients), this work identifies a novel depression biotype characterized by impaired visual motion perception, using machine learning clustering. An independent dataset confirms the robustness of this biotype through cross‐validation and demonstrates its generalizability.
Zhuoran Cai, Xi‐Wen Hu, Yuyang Li, Zheng Lin, Yongjie Li, Yong‐Chun Cai, Tao Xu, Ke Jia, Jin‐Fang Han, Zhong‐Lin Tan, Dezhong Yao, Xue Mei Song, Sugai Liang, Georg Northoff   +13 more
wiley   +1 more source

Epigenetic silencing of transposable elements by IRF2BP2 is a selective dependency of myeloid leukemia

Xu J, Whittle J, Clayfield L, Lie-a-ling M, Leddy EA, Smith D, Sellers R, Deniz O, Lacaud G.   +8 more
europepmc   +1 more source