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Transposable Elements and Cancer
1986Tumor progression is accompanied by many chromosomal aberrations and DNA rearrangements which contribute to the aggressiveness of the tumor. It is possible that active transposition of DNA elements play a role in these events. Approximately one third of the mammalian genome is composed of repetitive sequences (103 — 105 copies).
E, Arman +3 more
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Transposable Elements and Their Identification
2012Most genomes are populated by thousands of sequences that originated from mobile elements. On the one hand, these sequences present a real challenge in the process of genome analysis and annotation. On the other hand, there are very interesting biological subjects involved in many cellular processes.
Wojciech, Makałowski +3 more
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2008
Genomic programs are yielding tremendous amounts of data about plant genomes and their expression. In order to exploit and understand this data it will be necessary to determine the mechanisms leading to natural variation of patterns of gene expression.
Deragon, Jean-Marc +2 more
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Genomic programs are yielding tremendous amounts of data about plant genomes and their expression. In order to exploit and understand this data it will be necessary to determine the mechanisms leading to natural variation of patterns of gene expression.
Deragon, Jean-Marc +2 more
openaire +4 more sources
1991
Transposable elements were first detected in maize by Barbara McClintock and reported in the 1950s. These were revealed by experiments that were designed for a cytogenetic study involving the short arm of chromosome 9. It was in the progeny of plants undergoing the chromosomal type of breakage—fusion—bridge cycle that a burst of somatic instability and
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Transposable elements were first detected in maize by Barbara McClintock and reported in the 1950s. These were revealed by experiments that were designed for a cytogenetic study involving the short arm of chromosome 9. It was in the progeny of plants undergoing the chromosomal type of breakage—fusion—bridge cycle that a burst of somatic instability and
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Transposable Elements in Yeast
1983Publisher Summary Transposable elements are the DNA sequences that move to new genomic locations at a much higher rate than that of the bulk of the cellular DNA. The ability to cause deletions or chromosomal rearrangements is characteristic of these elements, and many have been shown to affect the expression of chromosomal genes by inserting adjacent
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Transposable Elements in Nematodes
1994Transposable elements are present in the genomes of most, if not all, organisms. Because of their ability to insert into and excise from the chromosomes of their hosts transposons are a significant source of spontaneous mutations in organisms. Therefore they can be used as a tool for cloning genes that have been identified by mutations and for which no
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Population Genetics of Transposable Elements
Mathematical Medicine and Biology, 1984Transposable elements are DNA sequences that can move or duplicatively transpose on the chromosome. A simple model of transposable elements was studied, and the frequency spectrum, allelism, and identity coefficients at equilibrium were obtained. In the analyses, the two cases of asexual haploid with no recombination and diploid with free recombination
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Transposable Elements in Eukaryotes
1985Publisher Summary This chapter classifies transposable elements according to their structure. It reviews some of the information available concerning transposable elements of each type. It also discusses some questions raised by transposable elements in general, particularly with regard to their biological significance and their possible use as ...
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