Results 221 to 230 of about 68,477 (364)
Transposon-based genome editing of industrial microorganisms: advances, challenges, and prospects. [PDF]
Zhang Z +5 more
europepmc +1 more source
Novel transposase tools for cell-line engineering
ATUM has discovered, characterized, engineered and patented new transposases that work comparable to, or better than previously commercialized transposases. The technology is highly valuable for protein expression and genome engineering applications.
Boldog, Ferenc +3 more
core
A stable genomic source of P element transposase in Drosophila melanogaster.
H. Robertson +5 more
semanticscholar +1 more source
Abstract Single‐cell multi‐omics sequencing technology provides a powerful tool for studying cellular heterogeneity. However, beyond the challenges of sparsity, heterogeneity, and dimensionality differences, a critical challenge in multi‐omics data integration lies in preserving the true regulatory relationships among molecular features.
Yucheng Lu, Xun Zhang, Hongwei Li
wiley +1 more source
Dissecting Pirtobrutinib Resistance in Mantle Cell Lymphoma Through Single‐Cell Multi‐Omics
ABSTRACT Pirtobrutinib (PBN), a non‐covalent BTK inhibitor, has been approved by the FDA for relapsed/refractory mantle cell lymphoma (MCL); however, resistance to PBN has been observed. To dissect the molecular dynamics driving PBN resistance, we performed integrative single‐cell multi‐omic profiling (scRNA‐seq, scATAC‐seq, and scDNA‐seq) on ...
Fangfang Yan +10 more
wiley +1 more source
Metabolism‐based atrazine‐resistant Amaranthus tuberculatus populations ACR and MCR exhibit little or no cross‐resistance to amicarbazone and metribuzin, suggesting that non‐halogenated Group 5 herbicides can be utilized to re‐establish effective control.
Alexander J Lopez +5 more
wiley +1 more source
Duplex-Indel: a Snakemake pipeline for somatic Indel calling in Tn5 transposase-based duplex sequencing data. [PDF]
Dong G +9 more
europepmc +1 more source
The C-terminal α Helix of Tn5 Transposase Is Required for Synaptic Complex Formation [PDF]
Mindy Steiniger-White +1 more
openalex +1 more source

