Technical Feasibility of a Murine Model of Sleeve Gastrectomy with Ileal Transposition [PDF]
Sleeve gastrectomy with ileal transposition has been shown to be superior to sleeve gastrectomy alone for promoting weight loss in rat and porcine models. The absence of a mouse model for this procedure has impeded efforts to understand the molecular physiology underlying its efficacy.
Lee D, Ying +5 more
openaire +2 more sources
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Pollution wash-off modelling on impervious surfaces: calibration, validation, transposition
This paper presents the modification and the application of the conceptual wash-off model initially proposed by the SWMM on five separate urban catchments with very different characteristics and during a lot of rainfall events. To allow measurements on real sites to be considered, this model was incorporated in an overall model including simulation ...
O. Scrivener +3 more
openaire +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Critical behavior of the S=1/2 Heisenberg ferromagnet: A Handscomb quantum Monte Carlo study
We investigate the critical relaxational dynamics of the S=1/2 Heisenberg ferromagnet on a simple cubic lattice within the Handscomb prescription on which it is a diagrammatic series expansion of the partition function that is computed by means of a ...
Costa, U. M. S. +2 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Competitive Assessments for HAP Delivery of Mobile Services in Emerging Countries
In recent years, network deployment based on High Altitude Platforms (HAPs) has gained momentum through several initiatives where air vehicles and telecommunications payloads have been adapted and refined, resulting in more efficient and less expensive ...
Gourhant, Yvon +2 more
core +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Algebraic Signal Processing Theory: Cooley-Tukey Type Algorithms for DCTs and DSTs
This paper presents a systematic methodology based on the algebraic theory of signal processing to classify and derive fast algorithms for linear transforms.
Moura, Jose M. F., Pueschel, Markus
core +3 more sources
THE META-DIDACTICAL TRANSPOSITION: A MODEL FOR ANALYSING TEACHERS EDUCATION PROGRAMS
This RF intends to continue the reflection developed in the RF "Teacher knowledge and teaching: viewing a complex relationship from three perspectives" by D. Ball, C.Y. Charalambous, M. Thames, & J.M. Lewis (PME 33, Thessaloniki, 2009). It presents Meta-Didactical Transposition, as a new model for framing teacher education projects that takes both the ...
Aldon G. +7 more
openaire +3 more sources

