Transposon-based genome editing of industrial microorganisms: advances, challenges, and prospects. [PDF]
Zhang Z +5 more
europepmc +1 more source
ABSTRACT Polyploidisation, creating redundant or diverged copies of the genome, is a major driving force in plant evolution, diversification and environmental adaptation, including for the kiwifruit genus (Actinidia Lindl.). We present a high‐contiguity, haplotype‐resolved genome assembly of the hexaploid Actinidia valvata rootstock cultivar ...
Miaomiao Lin +11 more
wiley +1 more source
Mining and engineering of active <i>PB</i> transposons in <i>Hymenoptera</i>. [PDF]
Wang B +6 more
europepmc +1 more source
ABSTRACT Sesame (Sesamum indicum L., 2n = 26) is one of the oldest oilseed crops and is often called the ‘queen of oilseeds’ due to its high content of unsaturated fatty acids and natural antioxidants. Despite its long history, the origin and global spread of cultivated sesame remain unresolved.
Weifei Yang +16 more
wiley +1 more source
Cas3-mediated genome reduction: demonstration in Cupriavidus necator H16 improves growth on heterotrophic and autotrophic carbon sources. [PDF]
Fulk EM +8 more
europepmc +1 more source
Understanding extracellular vesicles in antiaging
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad +3 more
wiley +1 more source
Comparative essentialome analysis of six <i>Pectobacteriaceae</i> strains using the TNSEEK pipeline identifies conserved and strain-specific fitness determinants. [PDF]
Baltenneck J +8 more
europepmc +1 more source
Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière +6 more
wiley +1 more source
Divergent Evolutionary Profile of <i>MULE</i> Transposons in Arthropods. [PDF]
Chen H +6 more
europepmc +1 more source
Progenitor Timing Shapes NG2‐Glia Fate and Oligodendrocyte Differentiation
Developmental timing defines NG2‐glia and oligodendrocyte fate. E16 NG2‐progenitors produce large, more dispersed NG2‐glia clones. P0 progenitors show a bias toward oligodendrocyte differentiation. Temporal windows establish long‐term cortical glial heterogeneity.
Ana Cristina Ojalvo‐Sanz +2 more
wiley +1 more source

