Results 181 to 190 of about 32,046 (240)

Catheter Ablation for Atrial Fibrillation in Cardiac Amyloidosis: A Systematic Review and Meta-Analysis. [PDF]

J Arrhythm
Sripusanapan A, Deepan N, Pongsukvechkul B, Kittiwongsopon S, Tan MC, Rattanawong P, Sorajja D, Shen WK, Chokesuwattanaskul R, Prasitlumkum N.   +9 more
europepmc   +1 more source

Pre-Amyloidosis Red-Flag Clinical Diagnoses in Light Chain (AL) Versus Age-Related Transthyretin (ATTRwt) Amyloidosis: Electronic Health Record-Based Descriptive Study. [PDF]

JMIR Med Inform
Estrada-Merly N, Pezzin LE, Sparapani R, D'Souza A.   +3 more
europepmc   +1 more source

Wild-Type Transthyretin Cardiac Amyloidosis Presenting As Progressive Heart Failure and Conduction Disease Despite Guideline-Directed Medical Therapy. [PDF]

Cureus
Richard S, Thomas D, Gorantla A, Devkota S, Graham-Hill S.   +4 more
europepmc   +1 more source

Effect of acoramidis on risk of death and heart problem-related hospitalizations in people with transthyretin amyloid cardiomyopathy: a plain language summary. [PDF]

Future Cardiol
Judge DP, Alexander KM, Cappelli F, Fontana M, Garcia-Pavia P, Grogan M, Hanna M, Masri A, Obici L, Soman P, Cao X, Lystig T, Tamby JF, Siddhanti S, Castaño A, Katz L, Fox JC, Mahaffey KW, Gillmore JD.   +18 more
europepmc   +1 more source

Gene silencing versus protein stabilization in transthyretin amyloid cardiomyopathy: contextualizing the HELIOS-B results and the road to precision agent selection. [PDF]

Ann Med Surg (Lond)
Khan SA, Ali T, Ul Haque MS, Qamar MA.
europepmc   +1 more source

Reply: Causal Inference Challenges in Evaluating Baroreflex Activation Therapy for Transthyretin Amyloid Cardiomyopathy: A Critical Appraisal. [PDF]

JACC Case Rep
Khanna NR, DenDulk A, Atteya G, Talati SN.   +3 more
europepmc   +1 more source

Clinical Factors Related to Cardiac Conduction Disturbance in Patients With Wild-Type Transthyretin Amyloid Cardiomyopathy Undergoing Tafamidis Treatment. [PDF]

Circ Rep
Hamamoto K, Kitagawa T, Okamoto D, Sada Y, Tatsugami F, Nakano Y.   +5 more
europepmc   +1 more source

Computational Studies on Transthyretin

Current Medicinal Chemistry, 2012
Among the 23 different fibril proteins described in human amyloidosis, transthyretin is associated with the most common hereditary form of the disease and its knowledge is corroborated through about 150 crystal structures in addition to thousands of small ligands tested as fibril formation inhibitors. In spite of the large amount of available data, the
ORTORE, GABRIELLA MARIA PIA, MARTINELLI, ADRIANO   +1 more
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Pathogenesis of transthyretin amyloidosis

Amyloid: the International Journal of Experimental and Clinical Investigation: the Official Journal of the International Society of Amyloidosis, 2012
Current dogma for transthyretin (TTR) pathogenesis is that mutations in TTR alter its structure such that the tetramer becomes unstable and prone to release of monomer which then becomes the putative building block of the fibril. This hypothesis is supported by thermodynamic data showing decreased stability of mutant TTR tetrameric proteins and ...
exaly   +3 more sources