Results 91 to 100 of about 18,049 (290)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Making all skills visible: the validation of transversal skills

open access: yes, 2023
Documento conclusivo relativo al progetto TRANSVAL-EU, co-finanziato dal Programma Erasmus+ dell’Unione Europea, Azione Chiave 3 – Policy Reform – Policy Experimentation e finalizzato allo sviluppo e sperimentazione di approcci innovativi per la ...
Cinti, Sonia
core  

Techniques for Transversal Skill Classification and Relevant Keyword Extraction from Job Advertisements

open access: yesInformation
The recognition of transversal skills from job ads is important for ensuring a proper match between potential candidates and the requirements formulated in job ad texts.
Marius Gavrilescu   +2 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Mesurer les compétences transversales des étudiants : apports et limites d’une grille d’autoévaluation

open access: yesMesure et Évaluation en Éducation, 2017
Cet article propose une réflexion sur les compétences transversales acquises ou mobilisées par les étudiants, à l’université ou en dehors du campus. La notion de transversalité considérée ici envisage la mobilisation de telles compétences au sein des ...
Julien Berthaud
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

How to support students to develop skills for planning and risk assessment

open access: yes
Engineering students encounter many team projects during their studies, yet rarely receive practical training on core project skills that they are expected to implement during their projects.
Schmid, Samuel   +3 more
core   +1 more source

Transversal skills in 7th grade mathematics tasks

open access: yes, 2021
Darba autors: Sarmīte Sagaloviča. Darba tēma: Caurviju prasmes 7. klases matemātikas uzdevumos. Darba veids: Bakalaura darbs. Studiju programma: Dabaszinātņu un informācijas tehnoloģijas skolotājs.
Sagaloviča, Sarmīte
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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