Results 101 to 110 of about 135,062 (303)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Experimenting with the design of policies on sustainable resource management : Progress report, June 4, 2004 [PDF]

, 2004
The overall objective of the DMP is to arrest land degradation in Africa's desert margins through demonstration and capacity building activities. The GEF increment to this project will enable the programme to address issues of global environmental ...
Leclerc, Grégoire
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Community Service Language Learning: From Practice to Research

Nouvelle Revue Synergies Canada
Based on an analysis of pedagogical practices, this article explains how community-based projects expand the learning space of university students enrolled in credit courses in French as a second language (FSL) or second language teaching (SLT ...
Laura Ambrosio
doaj   +1 more source

Desarrollo de actividades prácticas dirigidas a la adquisición de competencias profesionales [PDF]

, 2018
Most companies require engineering graduates with transversal skills, in addition to technical competences, for their professional practice. Therefore, regional, national and European engineering accreditation agencies pay special attention to the ...
Garrido-Balsells, José María, Reyes-Iglesias, Pedro Jose   +1 more
core  

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Investigating Transferable Skills in Early Childhood Education and Care PhD Programs in Norway and Greece

Nordic Journal of Comparative and International Education
The article investigates how transferable skills are defined, supported, and evidenced in Early Childhood Education and Care (ECEC) doctoral training in Norway and Greece.
Zacharias Andreadakis, Glykeria Fragkiadaki, Athanasios Gregoriadis, Elin Eriksen Ødegaard   +3 more
doaj   +1 more source

Online Scientific Volunteering: the technological immersion for the co-construction of knowledge, employability, entrepreneurship and innovation in a logic of inclusion [PDF]

, 2011
“We all have something to learn and something to share” is the motto of this project, through which we aim to assess the impact of a multilingual platform which combines and makes the most of the potentials of digital environments and favours inclusion ...
Barbas, Maria Potes, Cabrita, Isabel, Loureiro, Ana   +2 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

ANALYSIS OF FOREIGN LANGUAGE TEXTBOOKS IN TERMS OF TRANSVERSAL SKILLS

SOCIETY. INTEGRATION. EDUCATION. Proceedings of the International Scientific Conference, 2019
In Europe in the second half of the 20th century, events such as radical economic and social change, globalisation and its expression in culture, politics, the economy and the environment, and progress in scientific and information technology had an impact on education.
openaire   +1 more source