Results 51 to 60 of about 6,339 (174)

SPADE: A Deep Learning Framework for Spatial Mapping and Quantitative Cell–Cell Interaction Inference

Advanced Science, EarlyView.
SPADE integrates spatial transcriptomics with single‐cell RNA sequencing by using cell–cell communications (CCC) as a guide for spatial mapping. It improves cell‐type localization, enhances sparse gene‐expression signals, and reveals CCC programs at single‐spot resolution.
Xinyi Li, Ning Zhang, Zijie Jin
wiley   +1 more source

study

, 2021
Objectives This fetal MRI study aimed to characterize spatiotemporal growth differences of prenatal brainstem substructures and the cerebellum using linear biometry and planimetry.
Prayer, D., Kasprian, Gregor Johannes, Ulm, B., G. M. Gruber, V. Schmidbauer, G. J. Kasprian, Schmidbauer, V., Dovjak, G.O., M. Weber, M. Diogo, S. Glatter, G. O. Dovjak, Gruber, G.M., B. Ulm, Brugger, P.C., Diogo, M., Weber, M., P. C. Brugger, D. Prayer, Glatter, S.   +19 more
core   +1 more source

CHCHD10 Mitigates Alzheimer's Disease‐Related Phenotypes in Association With Epigenetic Remodeling in Directly Reprogrammed Neurons

Advanced Science, EarlyView.
CHCHD10 loss in Alzheimer's disease is associated with mitochondrial dysfunction, epigenomic disruption, and tau pathology. Restoration of CHCHD10 shifts DNA methylation toward a non‐disease state and reduces tau and amyloid pathology, with KATNAL2 acting as a downstream effector.
Teresa M. Thomas, Ching‐Yao Yang, Kexin Zhang, Liam Wetzel, Dina Bugybayeva, Julia Ferguson, Md Mahmudul Hasan, William Samsa, Nandita Patil, Anshul Dash, Tarini Gowda, Xiongwei Zhu, Feixiong Cheng, Tian Liu   +13 more
wiley   +1 more source

Accuracy of transverse cerebellar diameter measurement by ultrasonography in the evaluation of foetal age

, 2017
Background: Assessment of accurate gestational age of fetus is very imperative for proper obstetric management of normal as well as IUGR pregnancies. The objective of this study was to evaluate the accuracy of transverse cerebellar diameter as against ...
Nihar Reddy, Ravindernath M. L., Mahender Reddy   +2 more
core   +1 more source

Interobserver reproducibility of intracranial anatomy assessment during second trimester sonographic scan [PDF]

, 2021
To evaluate the reproducibility of mid-trimester intracranial anatomy assessment. Women undergoing mid-trimester scan (between 18th to 25th gestational weeks) for fetal anatomy assessment were included in the study. Measurements of lateral ventricle (LV),
Söylemez, Feride, KOÇ, FAİK ACAR, Kalafat, Erkan, Yüce, Tuncay, ÖZKAVUKCU, ESRA, ASLAN, BATUHAN   +5 more
core   +1 more source

Design, Control, and Clinical Applications of Magnetic Actuation Systems: Challenges and Opportunities

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This review aims to provide a broad understanding for interdisciplinary researchers in engineering and clinical applications. It addresses the development and control of magnetic actuation systems (MASs) in clinical surgeries and their revolutionary effects in multiple clinical applications.
Yingxin Huo, Lidong Yang, Tiantian Xu, Dong Sun   +3 more
wiley   +1 more source

Normal Standard TCD/AC Ratio for the Evaluation of Intrauterine Growth Restriction in Singleton Fetuses

Clinical and Experimental Obstetrics & Gynecology
Background: Intrauterine growth restriction is associated with increased fetal mortality rate, and its early detection is important for determining delivery timing and planning neonatal care.
Sung-Hee Yang, Dong-Yeon Lee
doaj   +1 more source

Research progress on biomarkers of traumatic brain injury

Animal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen, Si Cheng, Shuyi Chen, Mengyue Wang, Tangying Li, Weicheng Xu, Yifan Zhang, Ping Yuan, Lei Shi   +8 more
wiley   +1 more source

Cardiovascular Exercise Drives Neuroprotection in a Mouse Model of Spinocerebellar Ataxia 1 Via Rescue of Aberrant Splicing

Annals of Neurology, EarlyView.
Objective Spinocerebellar ataxia 1 (SCA1) is a fatal hereditary neurodegenerative disorder with no approved therapies, and gene‐targeting strategies have thus far failed in clinical trials. Exercise remains the only intervention shown to provide clinical benefit in patients with spinocerebellar ataxias (SCAs), yet the underlying mechanisms remain ...
Isabel Soto, Michael Bonomo, Brianna S. Nelthrope, Benjamin D. Carr, Emma Palmer, Mariana Sierra, Ilkim Erturk, David Peppercorn, Eleonor Cox, Tiare K. Vasconcellos, Henry L. Paulson, Hannah K. Shorrock, Sharan R. Srinivasan   +12 more
wiley   +1 more source

Evaluation of the Fetal Transverse Cerebellar Diameter (TCD) Measurement for Prediction of Gestational Age in 2nd and 3rd Trimesters of Pregnancy

, 2021
Background: To study the usefulness of transcerebellar diameter measurements ultrasonographically for detection gestational age as early period.  transcerebellar diameter with that determined by other parameter i.e.
Rehman, Khadija, Rizwan, Hafiz Muhammad, Naz, Hira, Ali, Sana   +3 more
core