Results 51 to 60 of about 10,975 (264)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Behavior of Short Columns Reinforced with Welded Wire Fabric as Transverse Reinforcement under Concentric Loading

Walailak Journal of Science and Technology, 2011
The purpose of this study was to investigate the behavior of concrete columns reinforced by Welded Wire Fabric, WWF, as transverse reinforcement under concentric loading and to compare the results with concrete columns reinforced by round bar as tie ...
Satjapan LEELATANON, Trakool ARAMRAKS
doaj   +1 more source

Research on the Estimation Model of Energy Consumption Capacity for Reinforced Concrete Components with Axial Force

Advances in Civil Engineering, 2023
The research group utilized the estimation model of energy consumption capacity for reinforced concrete components without axial force to assess the energy consumption capacity of 92-reinforced concrete components from the PEER database, which were ...
Yukui Wang, Shijun Yan, Dan Zhang, Zhangqi Hu   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Fire Behavior of Lightweight Reinforced Concrete Deep Beams and Enhanced Structural Performance via Varied Stirrup Spacing – An Integrated Study [PDF]

Journal of Rehabilitation in Civil Engineering
The behavior of lightweight reinforced concrete deep beams (LRCDBs) under fire conditions is investigated in this study, with a specific focus on the effect of varying transverse reinforcement spacing.
Ali Ali, Amir Akhaveissy, Bahaa Abbas
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Reinforced concrete beams coated with fiberglass-reinforced polymeric profiles as partial substitutes for the transverse reinforcement

Revista IBRACON de Estruturas e Materiais, 2020
: The use of GFRP (Glass Fiber Reinforced Polymers) structural profiles in the construction sector is growing due to their attractive properties, such as high mechanical strength and durability in aggressive environments.
Igor Souza Hoffman, Jorge Henrique Piva, Augusto Wanderlind, Elaine Guglielmi Pavei Antunes   +3 more
doaj   +1 more source

Visible Light Cure Fiber Frame Work Reinforcement of Acrylic Resin Denture Base Material. A Comparative Study. [PDF]

Al-Rafidain Dental Journal, 2014
Aims: Heat cured acrylic resin is the material of choice for construction of complete dentures due to its desirable properties, although it has some disadvantages as its susceptibility to fracture.
Aliaa W AL-Omari
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source