Results 61 to 70 of about 1,255,571 (298)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Geôle, enjôler, enjoliver : surveiller et (p)unir dans Lolita

Sillages Critiques, 2010
Nabokov writes in “On a book entitled Lolita” that the “initial shiver of inspiration” that triggered the composition of the novel was prompted by a newspaper story about an ape in the Jardin des Plantes which had produced a drawing representing the bars
René Alladaye
doaj   +1 more source

Optimized production of large Bose Einstein Condensates [PDF]

, 2006
We suggest different simple schemes to efficiently load and evaporate a ''dimple'' crossed dipolar trap. The collisional processes between atoms which are trapped in a reservoir load in a non adiabatic way the dimple.
Comparat, D., Dimova, E., Fioretti, A., Pillet, P., Stern, G., Tolra, B. Laburthe   +5 more
core   +2 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Adaptation “De Facto” ou Retour à l’Envoyer? L’Aide Déliée en Débat

Glocalism: Journal of Culture, Politics and Innovation, 2016
The debate on aid effectiveness has been going on for some time especially in an environment of budgetary pressure on the various economies of CAD (Comité d’Aide au Développement) countries.
Gino Vlavonou
doaj  

Towards surface quantum optics with Bose-Einstein condensates in evanescent waves

, 2008
We present a surface trap which allows for studying the coherent interaction of ultracold atoms with evanescent waves. The trap combines a magnetic Joffe trap with a repulsive evanescent dipole potential.
A. Aspect, A. Landragin, A.E. Avanasiev, C. Henkel, C. Henkel, C. Zimmermann, D. Rychtarik, F. Shimizu, H. Bender, H. Friedrich, H. Perrin, I. Dzyaloshinskii, J.-Y. Courtois, J.M. Obrecht, M. Fichet, M. Righini, M.A. Kasevich, P. Courteille, R.A. Cornelussen, S. Kallush, S. Slama, T. Passerat de Silans, T.A. Pasquini, V. Druzhinina, V. Sandoghdar, V. Savalli, V.I. Balyikin, Y.J. Lin   +27 more
core   +1 more source

AC electric trapping of neutral atoms [PDF]

, 2008
We study the dynamic behavior of ultracold neutral atoms in a macroscopic ac electric trap. Confinement in such a trap is achieved by switching between two saddle-point configurations of the electric field. The gradual formation of a stably trapped cloud
Adela Marian, Gerard Meijer, M. Morinaga, R. Grimm, Sophie Schlunk, W. Ketterle, Wieland Schöllkopf   +6 more
core   +3 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Field evaluation of effectiveness of the BG-Sentinel, a new trap for capturing adult Aedes aegypti (Diptera: Culicidae)

Memorias do Instituto Oswaldo Cruz, 2006
In recent years, the development of new tools to gather field information about vector ecological parameters has increased. This report evaluated the BG-Sentinel Trap (BGS-Trap), a promising new attempt to improve collection of the dengue vector, Aedes ...
Rafael Maciel-de-Freitas, Álvaro Eduardo Eiras, Ricardo Lourenço-de-Oliveira   +2 more
doaj   +1 more source