Results 111 to 120 of about 70,621 (279)

AllergoOncology in Review: Harnessing Allergy in the Field of Oncology to Improve Patient Outcomes

Clinical &Experimental Allergy, EarlyView.
ABSTRACT The AllergoOncology field brings together the study of allergic and cancer immune responses, having evolved from early epidemiological studies that reported inverse associations between allergies, IgE and cancer risk. Insights from studying allergic inflammation are revealing previously unappreciated immune mechanisms that confer protective ...
Jakub Zydron, Anishaa Balaji, Jitesh Chauhan, Jack Alder, Xinyi Chen, Anna M. F. Wiegman, Aurelie Poli, Joanna Jacków‐Malinowska, Jack Cheeseman, Daniel I. R. Spencer, James McDonnell, James Spicer, Alexandra J. McCraw, Sophia N. Karagiannis   +13 more
wiley   +1 more source

Intraocular Metastasis: Differential Diagnosis and Management

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Intraocular metastases represent the most common type of malignant intraocular tumour in adults. These commonly affect the choroid but can also involve the iris, ciliary body, retina, vitreous, optic disc or lens. Breast and lung cancer are the most common origins of intraocular metastases.
Genovefa Μachairoudia, Dimitrios Kazantzis, Guy S. Negretti, Mandeep S. Sagoo   +3 more
wiley   +1 more source

Sustained Clinical Benefit of Pyrotinib Combined with Capecitabine Rescue Therapy After Trastuzumab Resistance in HER2-Positive Advanced Gastric Cancer: A Case Report

, 2021
Xin Li, Xiaoqiang Gu, Jiahua Xu, Ling Chen, Hongwei Li, Dan Meng, Haoran Bai, Jinzu Yang, Jianxin Qian   +8 more
openalex   +2 more sources

Postexercise muscle oxygen uptake kinetics in older breast cancer survivors and healthy individuals: Association with myosteatosis

Experimental Physiology, EarlyView.
Abstract Reduced cardiorespiratory fitness is common among breast cancer survivors and, although traditionally attributed to cardiac dysfunction, might also be related to peripheral skeletal muscle abnormalities. We examined peak and submaximal plantar‐flexion exercise and recovery kinetics for lower‐leg oxygen uptake (V̇O2${\dot V_{{{\mathrm{O}}_2}}}$)
Nathan R. Weeldreyer, Thomas J. McMurtry, Stephen J. Foulkes, Amanda Shewman, Edith Pituskin, Rachel J. Skow, Richard B. Thompson, Justin Grenier, Deirdre E. O'Neill, Robert C. Welsh, Mark J. Haykowsky, Corey R. Tomczak   +11 more
wiley   +1 more source

Locally Advanced Synchronous Hemorrhagic Gastric Cancer—From the First Symptom to Therapy—Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Gastric cancer is one of the most common malignancies worldwide, and its incidence shows global variability, with the highest rates reported in Eastern Asia, Eastern Europe, and South America due to the aging population and growth of high‐risk groups.
Szabolcs Attila Gabor, Botond Istvan Kiss, Renata Moriczi, Evelyn Siklodi, Daniela Tatiana Sala, Radu Mircea Neagoe   +5 more
wiley   +1 more source

Trastuzumab and Doxorubicin-Related Cardiotoxicity and the Cardioprotective Role of Exercise

, 2009
Karen Y. Wonders, Beverly S. Reigle
openalex   +1 more source

Cardiac and cardiometabolic phenotyping of trastuzumab-mediated cardiotoxicity: a secondary analysis of the MANTICORE trial

, 2021
Amy A. Kirkham, Edith Pituskin, Richard B. Thompson, John R. Mackey, Sheri L. Koshman, Davinder S. Jassal, Marshall Pitz, Mark J. Haykowsky, Joseph J. Pagano, Kelvin Chow, Albert K.Y. Tsui, Justin A. Ezekowitz, Gavin Y. Oudit, D. Ian Paterson   +13 more
openalex   +2 more sources

147P Pharmacokinetics, safety, and efficacy of trastuzumab deruxtecan (T-DXd) with OATP1B/CYP3A inhibitors in patients with HER2-expressing advanced solid tumours [PDF]

, 2020
Masato Takahashi, Y-J. Bang, Masato Karayama, Junichiro Watanabe, Hironobu Minami, Noboru Yamamoto, Ichiro Kinoshita, C.-C. Lin, Y-H Im, T Fujiki, Issei Achiwa, Emi Kamiyama, Yasuyuki Okuda, C. Lee, Shunji Takahashi   +14 more
openalex   +1 more source

Optimizing Body Size‐Based Dosing Approaches for Antibody–Drug Conjugates

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 872-880, April 2026.
Optimized dosing precision of antibody–drug conjugates (ADCs) remains challenging due to narrow therapeutic indices, efficacious doses near the maximum tolerated dose, and substantial interindividual variability in exposure. Body size‐based dosing can reduce exposure variability when the allometric scaling exponent for clearance α = 1 but may over‐ or ...
Andrew B. SyBing, Diane D. Wang
wiley   +1 more source

Sex differences in genomics, immune microenvironment and immunotherapy response in adult grade 4 gliomas

Clinical and Translational Discovery, Volume 6, Issue 2, April 2026.
Overall survival of patients with brain tumors receiving ICIs treatment Abstract Purpose Sex differences in the prevalence of gliomas have been reported; however, whether there are sex differences in the development and immunotherapy of gliomas remains poorly understood.
Feng Tang, Zhen‐Yuan Liu, Xi Chen, Jin‐Zhou Yang, Zhi‐Qiang Li   +4 more
wiley   +1 more source