Results 161 to 170 of about 146,874 (392)

Optimizing the integration of modern systemic therapies and advanced radiotherapy techniques in breast cancer management: An expert opinion from the Institut Curie Breast Radiotherapy Group

open access: yesInternational Journal of Cancer, EarlyView.
Abstract The integration of modern systemic therapies with radiotherapy (RT) represents a promising strategy in breast cancer management, enhancing both locoregional control and systemic disease outcomes. This expert consensus from the Institut Curie Breast Radiotherapy Group focuses exclusively on modern systemic agents, synthesizing current evidence ...
Cezara Cheptea   +5 more
wiley   +1 more source

Positron Emission Tomography/Computed Tomography in Ovarian Cancer: Current Status and Future Potential

open access: yesiRADIOLOGY, EarlyView.
The role of PET/CT in the management of ovarian cancer at each disease stage, including primary detection, staging, prognosis evaluation, treatment response assessment and recurrence surveillance, and its future potential in relation to novel non‐FDG radiotracers, PET/MRI, dynamic PET and AI‐based radiomics.
Caiyun Xu   +4 more
wiley   +1 more source

Evaluation of HER2 Targeted Poly(Ethylene Glycol)‐Poly(L‐histidine) Copolymer Micelles in Breast Cancer Models

open access: yesMacromolecular Bioscience, EarlyView.
This study reports on the in vitro, ex vivo, and in vivo evaluation of HER2 targeted biodegradable micelle variants, conjugated with trastuzumab, with or without the drug doxorubicin or the dye rhodamine B. Findings indicate enhanced cellular association and efficacy of trastuzumab‐conjugated micelles in HER2 positive breast cancer models, showing ...
Remya Valsala Kumari   +11 more
wiley   +1 more source

Trastuzumab in the treatment of advanced breast cancer: Single-center experience [PDF]

open access: bronze, 2001
Mirando Mršić   +8 more
openalex   +1 more source

Vascularized Tumor‐on‐a‐Chip Model as a Platform for Studying Tumor‐Microenvironment‐Drug Interaction

open access: yesMacromolecular Bioscience, EarlyView.
Vascularized tumor‐on‐a‐chip platforms replicate human tumor microenvironments by integrating perfusable vessels and stromal elements in microfluidic systems. These models enable dynamic assessment of drug delivery and therapeutic response under physiologically relevant flow, offering enhanced predictive value for cancer treatment.
Hyelim Kim   +2 more
wiley   +1 more source

Correlation between resistance to trastuzumab and miR-141 relative expression in the BT-474 human breast cancer cell line

open access: yesمجله دانشگاه علوم پزشکی بیرجند, 2017
Background and Aim: Resistance to trastuzumab has been a critical barrier to targeted therapy of HER 2-positive (Human Epidermal Growth Factor Receptor 2) breast cancers.
Zohreh Rezaei   +3 more
doaj  

Astatine‐211—Towards In Vivo Stable Astatine‐211 Labeled Radiopharmaceuticals and Their (Pre)Clinical Applications

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Targeted radioligand therapy has emerged as a promising treatment option for eradicating advanced cancer forms. α‐Emitters are considered particularly promising as they can obliterate (micro)‐metastases. The α‐emitter astatine‐211 (211At) has experienced increased interest due to its favorable decay properties.
Marius Müller   +5 more
wiley   +1 more source

Targeting SLC7A11-mediated cysteine metabolism for the treatment of trastuzumab-resistant HER2-positive breast cancer

open access: yeseLife
Trastuzumab resistance remains a challenge for HER2-positive breast cancer treatment. Targeting metabolic reprogramming would provide novel insights for therapeutic strategies.
Yijia Hua   +13 more
doaj   +1 more source

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