Results 171 to 180 of about 152,178 (350)

Optimizing the integration of modern systemic therapies and advanced radiotherapy techniques in breast cancer management: An expert opinion from the Institut Curie Breast Radiotherapy Group

open access: yesInternational Journal of Cancer, Volume 158, Issue 7, Page 1775-1784, 1 April 2026.
Abstract The integration of modern systemic therapies with radiotherapy (RT) represents a promising strategy in breast cancer management, enhancing both locoregional control and systemic disease outcomes. This expert consensus from the Institut Curie Breast Radiotherapy Group focuses exclusively on modern systemic agents, synthesizing current evidence ...
Cezara Cheptea   +5 more
wiley   +1 more source

Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer.

open access: yesNew England Journal of Medicine, 2005
E. Romond   +24 more
semanticscholar   +1 more source

Delivering precision oncology in metastatic breast cancer: Clinical impact of comprehensive genomic profiling—The CATCH experience

open access: yesInternational Journal of Cancer, Volume 158, Issue 6, Page 1675-1689, 15 March 2026.
What's new? CATCH is a prospective precision oncology registry trial that harnesses whole‐genome/exome‐ and RNA‐sequencing to enable actionable biomarker detection in metastatic breast cancer patients of any subtype. The data of the first 412 consecutive patients with completed follow‐up in this real‐world, single‐center patient cohort provide robust ...
Mario Hlevnjak   +31 more
wiley   +1 more source

A phase II trial of dasatinib (D) in combination with trastuzumab (T) and paclitaxel (P) in the first line treatment of HER2 positive metastatic breast cancer (MBC) patients (pts): GEICAM/2010-04 [PDF]

open access: bronze, 2017
A. Ocana Fernandez   +19 more
openalex   +1 more source

Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer.

open access: yesNew England Journal of Medicine, 2005
M. Piccart-Gebhart   +31 more
semanticscholar   +1 more source

Addressing Causality and Homogeneity Assumptions in Exposure‐Response Analyses

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 3, Page 703-712, March 2026.
Exposure‐response, or pharmacokinetic–pharmacodynamic (PKPD), analyses support many drug development decisions. It is typically applied without assessment of causality and homogeneity, where the latter refers to the assumption that the reason for variability in exposure is unimportant for the impact on response.
Mats O. Karlsson, Divya Brundavanam
wiley   +1 more source

Trastuzumab Emtansine (T-DM1) in Patients (pts) With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Metastatic Breast Cancer (MBC): results From a Multicenter Retrospective Analysis [PDF]

open access: bronze, 2016
Laura Pizzuti   +19 more
openalex   +1 more source

Trastuzumab emtansine for HER2-positive advanced breast cancer.

open access: yesNew England Journal of Medicine, 2012
S. Verma   +13 more
semanticscholar   +1 more source

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