Results 101 to 110 of about 1,399,008 (302)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Penetrating Cardiac Trauma: Prognostic Factors

, 2007
RESUMEN: El pronóstico de los pacientes con herida de corazón depende del tipo y la magnitud de la lesión, el soporte prehospitalario y el estado clínico al ingresar a urgencias.
Cano Restrepo, Fidel, Rosero Cerón, Édgar, Ramírez Bedoya, Lina Maria, López Vélez, Marvin, Villegas Lanau, María Isabel, Bermúdez Posada, Luis Anibal, Benítez España, Gilberto, Morales Uribe, Carlos Hernando, Fernández Agudelo, Isabel Maria   +8 more
core  

Building a Clinical Research Network in Trauma Orthopaedics: The Major Extremity Trauma Research Consortium (METRC)

, 2016
OBJECTIVESLessons learned from battle have been fundamental to advancing the care of injuries that occur in civilian life. Equally important is the need to further refine these advances in civilian practice, so they are available during future conflicts.
Sims, Stephen H, Evans, Andrew R, Westberg, Jerald R, Wenke, Joseph C, Boateng, Henry A, Hayda, Roman A, Gary, Joshua, Sagi, H. Claude, Holthaus, Rachel, Maroto, Medardo R, Mann, Dennis W, Warlow, Pamela M, Watson, J. Tracy, Sciadini, Marcus F, Farrell, Dana J, Osborn, Patrick M, Lafferty, Paul M, Keeling, John, Silva, Heather, McKinley, Todd, Endres, Terrence J, De Lissovoy, Gregory, Marsh, J. Lawrence, Holden, Martha B, Langensiepen, Sarah B, Miclau, Theodore, Teasdall, Robert D, Henderson, Corey, Scharfstein, Daniel O, Hsu, Joseph R, Reid, J. Spence, Langford, Joshua, Boyd, Alysse J, Tornetta, Paul, Mir, Hassan R, Morshed, Saam, Russell, George, Karunakar, Madhav A, Hutson, James J, Nascone, Jason W, Frey, Katherine, Reider, Lisa, Allen, Lauren E, Carlini, Anthony, Teague, David C, Pollak, Andrew N, Firoozabadi, Reza, Carlisle, Hope, Patterson, Brendan M, Ceniceros, Xochitl, Zadnik-Newell, Mary, Carroll, Eben, Ficke, James R, Vallier, Heather A, Goodman, J. Brett, Jones, Clifford B, Unger, Daniel V, Cannada, Lisa K, Manson, Theodore T, Obremskey, William T, Karam, Matthew D, Keeney, James A, Sanders, Roy, Schmidt, Andrew, Smith, Lori, Toledano, James E, Carl, Kathy, Nelson, Amy, Stinner, Daniel, Seymour, Rachel B, Gordon, Wade, Kuhn, Kevin M, Franco, Kathy, Steverson, Barbara, Castillo, Renan C, MacKenzie, Ellen J, Churchill, Christine, Smith, Christopher, Archer, Kristin R, Gissel, Hannah, Rodriguez, Dinorah, Chan, Daniel S, Bergin, Patrick F, Sangeorzan, Bruce, Belaye, Tigist, Gaski, Greg, Sietsema, Debra L, Burgess, Andrew R, Molina, Cesar S, Westerlind, Brian O, Mazurek, Michael T, O'Toole, Robert, Harriott, Paula, Hak, David J, Wells, Janet, Bosse, Michael J, Zych, Gregory A   +96 more
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Improving care and equity in the American trauma system: past, present and future

Trauma Surgery & Acute Care Open
Trauma care in the USA is fragmented, unequal, and millions of people lack adequate access to a trauma center. These inequities are the result of historic precedent, racial and socioeconomic discrimination, and the economics of trauma care.
Dane R Scantling, Sophia Smith
doaj   +1 more source

Trauma-Informed Care Implementation in Texas Community Health Centers: Results of Organizational Assessments

OBJECTIVE: Trauma-informed care (TIC) recognizes the impact of trauma on health and is suitable for implementation in health care settings to foster improved staff and patient outcomes.
Sheela Raja (10639700), Paula M Cuccaro (23804620), Qiheng Yan (23804608), Rachel Barnes (20391180), Aimee Rachel (23804611), Jihye Choi (2131255), Jenny Niedenfuehr (23804617), Efrat K Gabay (23804614)   +7 more
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Trauma Center Staffing, Infrastructure, and Patient Characteristics that Influence Trauma Center Need

Western Journal of Emergency Medicine, 2014
Introduction: The most effective use of trauma center resources helps reduce morbidity and mortality, while saving costs. Identifying critical infrastructure characteristics, patient characteristics and staffing components of a trauma center associated ...
Faul, Mark, Sasser, Scott M., Lairet, Julio, Mould-Millman, Nee-Kofi, Sugerman, David   +4 more
doaj   +1 more source

Extracorporeal life support in pediatric trauma: a systematic review [PDF]

, 2019
Introduction Extracorporeal membrane oxygenation (ECMO) was once thought to be contraindicated in trauma patients, however ECMO is now used in adult patients with post-traumatic acute respiratory distress syndrome (ARDS) and multisystem trauma ...
Puzio, Thaddeus, Murphy, Patrick, Phillips, Michael, Cotton, Bryan A., Gazzetta, Josh, Hartwell, Jennifer L.   +5 more
core   +1 more source