Results 151 to 160 of about 148,445 (286)

Veterans Traumatic Brain Injuries and Neurosurgical Challenges: A Narrative Review. [PDF]

Health Sci Rep
Mortezaei A, Safari N, Gholamshahi H, Kazemzadeh K, Tafakhori A.   +4 more
europepmc   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

Severe Traumatic Brain Injuries and Associated Outcomes at a Level 1 Trauma Center. [PDF]

Biomedicines
Sharma B, Patel T, Al-Ali H, Agriantonis G, Bhatia ND, Garcia C, Nesamony P, Dave J, Mestre J, Arora S, Bhatti S, Shafaee Z, Phalakornkul S, Twelker K, Whittington J.   +14 more
europepmc   +1 more source

Early outcomes of a community‐based participatory research (CBPR) approach to investigating brain health and ADRD phenotypes following traumatic brain injury [PDF]

Kristen Dams-O’Connor
openalex   +1 more source

Introduction. Traumatic brain injury [PDF]

Neurosurgical Focus, 2019
Alex B, Valadka, Andrew I R, Maas, Franco, Servadei   +2 more
openaire   +2 more sources

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Characteristics, Context and Injury Mechanism of Traumatic Brain Injuries at Laquintinie Hospital in Douala: An In-Depth Analysis Over 5 Years. [PDF]

Korean J Neurotrauma
Blaise MH, Haman NO, Renee BA, Orlane NT, Ben DO, Figuim B, De Paul DV.   +6 more
europepmc   +1 more source

Perceived Social Support and Psychological Well-being in Caregivers of Traumatic Brain Injury Patients: A Descriptive Study [PDF]

Malathi Dhakshnamoorthy -, Sankaran Rajendran, Duraikannu Anandhi -, Kannan Kasinathan -, Athya Farheen Mohammed Sulthan, Padmanabhan Murugan   +5 more
openalex   +1 more source

Disrupting CSPG‐Driven Microglia–Astrocyte Crosstalk Enables Scar‐Free Repair in Spinal Cord Injury

Advanced Science, EarlyView.
This study identifies CSPGs as key drivers of glial scar maturation after spinal cord injury by reprogramming microglial metabolism and inducing astrocyte fibrosis. To address this, a reactive oxygen species‐responsive, reactive astrocyte‐targeted ChABC gene delivery system is designed to locally degrade CSPGs, precisely disrupt maladaptive glial ...
Yufei Zheng, Zhaowei Zhang, Zezhou Fu, Qingqing Wang, Siwen Zhang, Tingyu Zhang, Meifei Zhu, Shunwu Fan, Youqing Shen, Jiajia Xiang, Xin Liu   +10 more
wiley   +1 more source

Upper Limb Movement Performance in Individuals Sustaining Mild Traumatic Brain Injuries. [PDF]

Ann Neurosci
Subramanian SK, Gonzalez EA, Villalpando L, Chavez MD, Mezulic DS, Verduzco-Gutierrez M.   +5 more
europepmc   +1 more source