Results 1 to 10 of about 559,838 (180)

The synapse in traumatic brain injury [PDF]

Brain, 2020
Traumatic brain injury is a leading cause of death and disability and is a risk factor for dementia later in life. Jamjoom et al. review the role of the synapse in TBI pathophysiology with a focus on the confluence of secondary injury processes including
A. Jamjoom, J. Rhodes, P. Andrews, S. Grant   +3 more
semanticscholar   +5 more sources

Diffuse axonal injury predicts neurodegeneration after moderate-severe traumatic brain injury [PDF]

Brain : a journal of neurology, 2020
Traumatic brain injury is associated with elevated rates of neurodegenerative diseases such as Alzheimer's disease and chronic traumatic encephalopathy. In experimental models, diffuse axonal injury triggers post-traumatic neurodegeneration, with axonal ...
Bourke, NJ, Cole, JH, Graham, NSN, Jolly, A, Schott, JM, Scott, G, Sharp, DJ, Zimmerman, K   +7 more
core   +5 more sources

Experimental traumatic brain injury [PDF]

Experimental & Translational Stroke Medicine, 2010
Traumatic brain injury, a leading cause of death and disability, is a result of an outside force causing mechanical disruption of brain tissue and delayed pathogenic events which collectively exacerbate the injury.
A Bordey, A Marmarou, A Pitkanen, A Quintana, A Spain, AI Faden, AI Maas, AJ McLean, AL Morrison, AL Siren, Anna-Leena Sirén, AW Unterberg, B Morrison, B Nilsson, BJ Kelley, BM Bellander, C Israelsson, C Lindh, C Mock, C Redecker, C Tengvar, CE Dixon, CE Dixon, Christiane Albert-Weissenberger, CL Floyd, D Tweedie, DC Viano, DH Smith, DH Smith, DH Smith, DI Shreiber, Division of Injury Response, National Center for Injury Prevention and Control Centers for Disease Control and Prevention, U.S Department of Health and Human Services, DJ Myer, DM Feeney, DM Morales, DR Richmond, E Lewin, E Shohami, E Shohami, ED Hall, EM Doppenberg, ET Martins, F Raslan, G Rakos, G Umschwief, G Yattoo, GG Rogatsky, GS Griesbach, GV Allen, H Goldman, H Nawashiro, H Tanno, HC Wang, HD Soares, HJ Thompson, HM Pappius, HS Dhillon, I Cernak, I Cernak, I Cernak, I Leinhase, I Leinhase, J Coutinho-Netto, J Eriskat, J Isaksson, JE Levasseur, JE Pierce, JY Ding, K Maruichi, KC McNamara, KD Hall, KD Statler, KD Statler, KL Keeling, KL Kiening, L Venturi, L von Baumgarten, M Blaha, M Gaetz, M Giralt, M Kilbourne, M Koshinaga, M Maegele, M Penkowa, M Penkowa, M Stoffel, MA Flierl, MA Foda, MB Elliott, MJ McGinn, MK Baskaya, MK Baskaya, MT Fitch, MU Schuhmann, MW Uhl, N Ishige, N Murakami, O Zohar, P Mathew, P Nilsson, P Pifarre, PD Adelson, PD Adelson, R Sandhir, R Stroop, R Vink, RF Hunt, S Holmin, S Hoshino, S Mikawa, S Miyazaki, S Mori, SF Chen, ST DeKosky, T Igarashi, T Yamaki, T Yamaki, T Yamaki, TK McIntosh, TK McIntosh, V Tashlykov, WG Dail, WS Carbonell, WS Carbonell, WT Chiu, Y Chen, Y Shapira, Y Xiong, Y Yanagida   +128 more
core   +7 more sources

Traumatic Brain Injury [PDF]

Veterinary Pathology, 2002
Animal models have played a critical role in elucidating the complex pathogenesis of traumatic brain injury, the major cause of death and disability in young adults in Western countries. This review discusses how different types of animal models are useful for the study of neuropathologic processes in traumatic, blunt, nonmissile head injury.
Finnie, J., Blumbergs, P.
  +10 more sources

Traumatic brain injuries [PDF]

Nature Reviews Disease Primers, 2016
Traumatic brain injuries (TBIs) are clinically grouped by severity: mild, moderate and severe. Mild TBI (the least severe form) is synonymous with concussion and is typically caused by blunt non-penetrating head trauma. The trauma causes stretching and tearing of axons, which leads to diffuse axonal injury - the best-studied pathogenetic mechanism of ...
Gerard M. Ribbers, Patrick M. Kochanek, Kristine Yaffe, David L. Brody, Kaj Blennow, Henrik Zetterberg, Henrik Zetterberg, Henrik Zetterberg, Ann C. McKee, Harvey S. Levin   +9 more
openaire   +8 more sources

Traumatic brain injury [PDF]

CNS Neuroscience & Therapeutics, 2020
A head trauma is any injury that results in trauma to the skull, scalp, or brain. Every patient with a suspected head trauma should initially undergo a focused neurological examination which consists of the Glasgow Coma Scale Score (GCS), plus pupillary reactivity, that classifies the traumatic brain injury (TBI) as mild, moderate, or severe.
Julian E. Bailes, Cesar V. Borlongan
openaire   +4 more sources

Traumatic brain injury [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2011
There is an increasing incidence of military traumatic brain injury (TBI), and similar injuries are seen in civilians in war zones or terrorist incidents. Indeed, blast-induced mild TBI has been referred to as the signature injury of the conflicts in Iraq and Afghanistan.
Jane E. Risdall, David K. Menon
openaire   +6 more sources

Determinants of recovery after traumatic brain injury:a neuropsychological perspective on symptoms across the severity spectrum [PDF]

, 2022
Annually, approximately 85.000 people in the Netherlands sustain a traumatic brain injury, also known as a concussion (mild traumatic brain injury) or a contusion (moderate to severe traumatic brain injury).
Rakers, Sandra Elisabeth
core   +1 more source

Traumatic brain injury [PDF]

Neurology, 2010
In the article “A Prospective Diffusion Tensor Imaging Study in Mild Traumatic Brain Injury” ( Neurology ® 2010;74:643–650), Andrew Mayer and colleagues studied the effects of mild brain injury using a special kind of magnetic resonance image (MRI). The new MRI sequence is called diffusion tensor imaging (DTI).
Steven Karceski, Emily J. Gilmore
openaire   +3 more sources

Epidemiology of Chronic Effects of Traumatic Brain Injury

Journal of Neurotrauma, 2021
Although many patients diagnosed with traumatic brain injury (TBI), particularly mild TBI, recover from their symptoms within a few weeks, a small but meaningful subset experience symptoms that persist for months or years after injury and significantly ...
J. Haarbauer-Krupa, M. Pugh, E. Prager, Nicole Harmon, J. Wolfe, K. Yaffe   +5 more
semanticscholar   +1 more source