Results 1 to 10 of about 704,420 (419)
The synapse in traumatic brain injury [PDF]
Brain, 2020 Traumatic brain injury is a leading cause of death and disability and is a risk factor for dementia later in life. Jamjoom et al. review the role of the synapse in TBI pathophysiology with a focus on the confluence of secondary injury processes including
A. Jamjoom +3 more
semanticscholar +5 more sources
Veterinary Pathology, 2002 Animal models have played a critical role in elucidating the complex pathogenesis of traumatic brain injury, the major cause of death and disability in young adults in Western countries. This review discusses how different types of animal models are useful for the study of neuropathologic processes in traumatic, blunt, nonmissile head injury.
Finnie, J., Blumbergs, P.
+10 more sources
Traumatic brain injuries [PDF]
Nature Reviews Disease Primers, 2016 Traumatic brain injuries (TBIs) are clinically grouped by severity: mild, moderate and severe. Mild TBI (the least severe form) is synonymous with concussion and is typically caused by blunt non-penetrating head trauma. The trauma causes stretching and tearing of axons, which leads to diffuse axonal injury - the best-studied pathogenetic mechanism of ...
Gerard M. Ribbers +9 more
openaire +8 more sources
CNS Neuroscience & Therapeutics, 2020 A head trauma is any injury that results in trauma to the skull, scalp, or brain. Every patient with a suspected head trauma should initially undergo a focused neurological examination which consists of the Glasgow Coma Scale Score (GCS), plus pupillary reactivity, that classifies the traumatic brain injury (TBI) as mild, moderate, or severe.
Julian E. Bailes, Cesar V. Borlongan
openaire +4 more sources
Philosophical Transactions of the Royal Society B: Biological Sciences, 2011 There is an increasing incidence of military traumatic brain injury (TBI), and similar injuries are seen in civilians in war zones or terrorist incidents. Indeed, blast-induced mild TBI has been referred to as the signature injury of the conflicts in Iraq and Afghanistan.
Jane E. Risdall, David K. Menon
openaire +6 more sources
Di-san junyi daxue xuebao, 2021 Objective To analyze the influencing factors for tracheostomy decannulation in patients with prolonged disorders of consciousness. Methods Clinical data of 59 cases with prolonged disorders of consciousness and having undergone tracheotomy in Guangdong ...
HE Yanbin +4 more
doaj +1 more source
Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1926-1940, December 2022., 2022 Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh +5 more
wiley +1 more source
Clusters of conditions among US service members diagnosed with mild TBI from 2017 through 2019
Frontiers in Neurology, 2022 BackgroundMany US Military Service Members (SMs) newly diagnosed with mild Traumatic Brain Injury (mTBI) may exhibit a range of symptoms and comorbidities, making for a complex patient profile that challenges clinicians and healthcare administrators ...
Tajrina Hai +4 more
doaj +1 more source
Scientific Reports, 2022 Traumatic brain injury (TBI) can be associated with long-term neurobehavioral symptoms. Here, we examined levels of neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP) in extracellular vesicles isolated from blood, and their ...
Vivian A. Guedes +16 more
doaj +1 more source
Research progress on cerebrospinal fluid markers in traumatic brain injury
Chinese Journal of Contemporary Neurology and Neurosurgery, 2023 The pathophysiological mechanism of traumatic brain injury (TBI) is complex, and the changes of cerebrospinal fluid markers can reflect the changes of brain microenvironment and neurometabolic processes, and are not easily interfered by peripheral ...
LIU Jun, ZHANG Guo⁃bin
doaj +1 more source