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Veterinary Pathology, 2002 Animal models have played a critical role in elucidating the complex pathogenesis of traumatic brain injury, the major cause of death and disability in young adults in Western countries. This review discusses how different types of animal models are useful for the study of neuropathologic processes in traumatic, blunt, nonmissile head injury.
Finnie, J., Blumbergs, P.
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Traumatic brain injuries [PDF]
Nature Reviews Disease Primers, 2016 Traumatic brain injuries (TBIs) are clinically grouped by severity: mild, moderate and severe. Mild TBI (the least severe form) is synonymous with concussion and is typically caused by blunt non-penetrating head trauma. The trauma causes stretching and tearing of axons, which leads to diffuse axonal injury - the best-studied pathogenetic mechanism of ...
Gerard M. Ribbers +9 more
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CNS Neuroscience & Therapeutics, 2020 A head trauma is any injury that results in trauma to the skull, scalp, or brain. Every patient with a suspected head trauma should initially undergo a focused neurological examination which consists of the Glasgow Coma Scale Score (GCS), plus pupillary reactivity, that classifies the traumatic brain injury (TBI) as mild, moderate, or severe.
Julian E. Bailes, Cesar V. Borlongan
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Philosophical Transactions of the Royal Society B: Biological Sciences, 2011 There is an increasing incidence of military traumatic brain injury (TBI), and similar injuries are seen in civilians in war zones or terrorist incidents. Indeed, blast-induced mild TBI has been referred to as the signature injury of the conflicts in Iraq and Afghanistan.
Jane E. Risdall, David K. Menon
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Di-san junyi daxue xuebao, 2021 Objective To analyze the influencing factors for tracheostomy decannulation in patients with prolonged disorders of consciousness. Methods Clinical data of 59 cases with prolonged disorders of consciousness and having undergone tracheotomy in Guangdong ...
HE Yanbin +4 more
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Clusters of conditions among US service members diagnosed with mild TBI from 2017 through 2019
Frontiers in Neurology, 2022 BackgroundMany US Military Service Members (SMs) newly diagnosed with mild Traumatic Brain Injury (mTBI) may exhibit a range of symptoms and comorbidities, making for a complex patient profile that challenges clinicians and healthcare administrators ...
Tajrina Hai +4 more
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Research progress on cerebrospinal fluid markers in traumatic brain injury
Chinese Journal of Contemporary Neurology and Neurosurgery, 2023 The pathophysiological mechanism of traumatic brain injury (TBI) is complex, and the changes of cerebrospinal fluid markers can reflect the changes of brain microenvironment and neurometabolic processes, and are not easily interfered by peripheral ...
LIU Jun, ZHANG Guo⁃bin
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Scientific Reports, 2022 Traumatic brain injury (TBI) can be associated with long-term neurobehavioral symptoms. Here, we examined levels of neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP) in extracellular vesicles isolated from blood, and their ...
Vivian A. Guedes +16 more
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Chinese Journal of Contemporary Neurology and Neurosurgery, 2023 Objective To evaluate the correlation between bispectral index (BIS) and the prognosis of patients with spontaneous intracerebral hemorrhage (sICH). Methods Sixty ⁃ four patients with sICH admitted to intensive care unit after surgery in Tianjin Huanhu ...
ZHANG Lei, ZHANG Tao
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Neurology, 2010 In the article “A Prospective Diffusion Tensor Imaging Study in Mild Traumatic Brain Injury” ( Neurology ® 2010;74:643–650), Andrew Mayer and colleagues studied the effects of mild brain injury using a special kind of magnetic resonance image (MRI). The new MRI sequence is called diffusion tensor imaging (DTI).
Steven Karceski, Emily J. Gilmore
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