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Current Opinion in Critical Care, 2003
Management of the patient with traumatic brain injury is a rapidly advancing field, characterized in recent years by an improved understanding of intracranial pathophysiology and ways in which outcomes can be improved. Many traditional therapies, such as fluid restriction and hyperventilation, have been called into question and are no longer ...
Richard P. Dutton, Maureen McCunn
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Management of the patient with traumatic brain injury is a rapidly advancing field, characterized in recent years by an improved understanding of intracranial pathophysiology and ways in which outcomes can be improved. Many traditional therapies, such as fluid restriction and hyperventilation, have been called into question and are no longer ...
Richard P. Dutton, Maureen McCunn
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Seminars in Neurology, 2015
Traumatic brain injury (TBI) is a major cause of traumatic death and disability In the US, a brain injury occurs every 7 s and results in death every 5 min ∼52,000 patients die from TBI each year TBI accounts for nearly one-third of all trauma-related deaths Common mechanisms include falls, motor vehicle accidents, and assaults In the US, most TBIs are
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Traumatic brain injury (TBI) is a major cause of traumatic death and disability In the US, a brain injury occurs every 7 s and results in death every 5 min ∼52,000 patients die from TBI each year TBI accounts for nearly one-third of all trauma-related deaths Common mechanisms include falls, motor vehicle accidents, and assaults In the US, most TBIs are
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Emergency Medicine Clinics of North America, 1996
Traumatic brain injury (TBI) contributes significantly to the mortality and morbidity rates of traumatized patients. This article presents current concepts in the pathophysiology of TBI, including mechanisms of injury, biomolecular mediators of injury, and the occurrence of secondary injury. Emergency management, monitoring, and imaging of TBI also are
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Traumatic brain injury (TBI) contributes significantly to the mortality and morbidity rates of traumatized patients. This article presents current concepts in the pathophysiology of TBI, including mechanisms of injury, biomolecular mediators of injury, and the occurrence of secondary injury. Emergency management, monitoring, and imaging of TBI also are
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Pharmacology of traumatic brain injury
Current Opinion in Pharmacology, 2003The intensity of experimental and clinical research to identify a neuroprotective drug for the treatment of traumatic brain injury is motivated by the devastating morbidity and mortality of this condition. Encouraging experimental work has led so far to disappointing clinical trials and the identification of new potential therapeutic targets is ...
Royo, N C +4 more
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Neuroprotection in traumatic brain injury
Drug Discovery Today, 2008The management of traumatic brain injury (TBI) is challenging and there is a need for neuroprotective therapies. A better understanding of the pathomechanism of TBI, particularly of the evolution of secondary damage, is providing targets for new approaches and selected ones in clinical development are described.
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Bromocriptine in traumatic brain injury
Brain Injury, 2006The authors report the case of a 63-year-old patient with severe traumatic brain injury (TBI) associated with Parkinson's syndrome, whose performances were dramatically improved by bromocriptine therapy, with an improvement of the scores, not only on tests evaluating motor functions but also on tests evaluating the patient's cognitive functions ...
Ben Smaïl, Djamel +4 more
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Neurologic Clinics
Advances in trauma care have allowed persons with traumatic brain injury to survive at increasingly greater rates. However, they commonly go on to experience complex symptoms including changes in cognitive, emotional, and behavioral functioning that together limit functioning and quality of life.
Thomas F, Bergquist +2 more
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Advances in trauma care have allowed persons with traumatic brain injury to survive at increasingly greater rates. However, they commonly go on to experience complex symptoms including changes in cognitive, emotional, and behavioral functioning that together limit functioning and quality of life.
Thomas F, Bergquist +2 more
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2016
Traumatic brain injury (TBI) results in short and long-term mental health syndromes that can affect patients for years after injury. The mental health disorders associated with moderate to severe brain trauma have been well established, but emerging evidence clearly suggests that even mild injuries can lead to transient and/or permanent disabilities in
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Traumatic brain injury (TBI) results in short and long-term mental health syndromes that can affect patients for years after injury. The mental health disorders associated with moderate to severe brain trauma have been well established, but emerging evidence clearly suggests that even mild injuries can lead to transient and/or permanent disabilities in
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DeckerMed Surgery, 2018
Traumatic brain injury remains a leading cause of death and disability worldwide. Patients with severe traumatic brain injury are best treated with a multidisciplinary, evidence-based, protocol-directed approach, which has been shown to decrease mortality and improve functional outcomes.
Marike Zwienenberg +4 more
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Traumatic brain injury remains a leading cause of death and disability worldwide. Patients with severe traumatic brain injury are best treated with a multidisciplinary, evidence-based, protocol-directed approach, which has been shown to decrease mortality and improve functional outcomes.
Marike Zwienenberg +4 more
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Sleep and Traumatic Brain Injury
Sleep Medicine Clinics, 2016Post-traumatic sleep-wake disturbances are frequent and often chronic complications after traumatic brain injury. The most prevalent sleep-wake disturbances are insomnia, excessive daytime sleepiness, and pleiosomnia, (i.e., increased sleep need).
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