Working toward exposure thresholds for blast-induced traumatic brain injury: thoracic and acceleration mechanisms [PDF]
Research in blast-induced lung injury resulted in exposure thresholds that are useful in understanding and protecting humans from such injury. Because traumatic brain injury (TBI) due to blast exposure has become a prominent medical and military problem, similar thresholds should be identified that can put available research results in context and ...
arxiv +1 more source
An update on diagnostic and prognostic biomarkers for traumatic brain injury
Introduction: Traumatic brain injury (TBI) is a major worldwide neurological disorder of epidemic proportions. To date, there are still no FDA-approved therapies to treat any forms of TBI.
Kevin K. W. Wang+6 more
semanticscholar +1 more source
Amyloid-β and tau deposition in traumatic brain injury: a study of Vietnam War veterans [PDF]
Traumatic brain injury is widely viewed as a risk factor for dementia, but the biological mechanisms underlying this association are still unclear. In previous studies, traumatic brain injury has been associated with the hallmark pathologies of Alzheimer’
Bruin, Hannah de+8 more
core +1 more source
Catecholamines and cognition after traumatic brain injury [PDF]
Cognitive problems are one of the main causes of ongoing disability after traumatic brain injury. The heterogeneity of the injuries sustained and the variability of the resulting cognitive deficits makes treating these problems difficult. Identifying the
Jenkins, PO, Mehta, MA, Sharp, DJ
core +2 more sources
Pathophysiology of traumatic brain injury.
The knowledge of the pathophysiology after traumatic head injury is necessary for adequate and patient-oriented treatment. As the primary insult, which represents the direct mechanical damage, cannot be therapeutically influenced, target of the treatment
C. Werner, K. Engelhard
semanticscholar +1 more source
Traumatic Brain Injury and Hypopituitarism [PDF]
Results of recent and ongoing studies have made it clear that brain injuries like Traumatic Brian Injury (TBI) pose substantial risk to pituitary function, perhaps even greater risk than previously believed. Patients with TBI should be screened both prospectively and retrospectively for isolated, multiple and even total pituitary deficits.
AIMARETTI G., GHIGO, Ezio
openaire +5 more sources
Neuroimaging of Traumatic Brain Injury [PDF]
The purpose of this article is to review conventional and advanced neuroimaging techniques performed in the setting of traumatic brain injury (TBI). The primary goal for the treatment of patients with suspected TBI is to prevent secondary injury. In the setting of a moderate to severe TBI, the most appropriate initial neuroimaging examination is a ...
David B. Douglas+10 more
openaire +5 more sources
A Thoracic Mechanism of Mild Traumatic Brain Injury Due to Blast Pressure Waves [PDF]
The mechanisms by which blast pressure waves cause mild to moderate traumatic brain injury (mTBI) are an open question. Possibilities include acceleration of the head, direct passage of the blast wave via the cranium, and propagation of the blast wave to the brain via a thoracic mechanism.
arxiv +1 more source
Concussion classification via deep learning using whole-brain white matter fiber strains [PDF]
Developing an accurate and reliable injury predictor is central to the biomechanical studies of traumatic brain injury. State-of-the-art efforts continue to rely on empirical, scalar metrics based on kinematics or model-estimated tissue responses explicitly pre-defined in a specific brain region of interest.
arxiv +1 more source
Acceptance and commitment therapy delivered in a dyad after a severe traumatic brain injury: a feasibility study [PDF]
Objective: There is a high prevalence of complex psychological distress after a traumatic brain injury but limited evidence of effective interventions.
Ciarrochi, Joseph V.+4 more
core +1 more source