Results 61 to 70 of about 678,664 (295)

Vaccine-associated measles in a patient treated with natalizumab: a case report

BMC Infectious Diseases, 2020
Background Safety of live vaccines in patients treated with immunosuppressive therapies is not well known, resulting in contradictory vaccination recommendations.
Alix Miauton, Rainer Tan, Vasiliki Pantazou, Renaud Du Pasquier, Blaise Genton   +4 more
doaj   +1 more source

Travel to Work, Travel to Play: On Russian Tourism, Travel, and Leisure [PDF]

Slavic Review, 2003
In the introduction to this special issue, Diane P. Koenker discusses the interrelated categories of travel, tourism, and leisure, looking at contrasting definitions of the traveler and the tourist and situating Russian and Soviet experience in a broader literature. Among the themes raised in the issue's articles, she enumerates the quest for knowledge
openaire   +3 more sources

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

FEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter, James Larson, Monika Tokmina‐Lukaszewska, Jin Xiong, Jared Green, Yisong Guo, William E. Broderick, Brian Bothner, Joan B. Broderick   +8 more
wiley   +1 more source

Perforation Peritonitis at High Altitude

Journal of Nepal Medical Association, 2018
Trekkers going to high altitude can suffer from several ailments both during and after their treks. Gastro-intestinal symptoms including nausea, vomiting, and abdominal pain are common in high altitude areas of Nepal due to acute mountain sickness or due
Bhawana Amatya, Paleswan Joshi Lakhey, Prativa Pandey   +2 more
doaj   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source

The Enlightenment of Travel

Journal of the American College of Cardiology, 2008
![Figure][1] I write this Editor's Page on the last leg of a trip taken to Asia to attend several medical conferences. Actually, the bulk of the time was spent in Vietnam. It is said that travel is very broadening.
openaire   +3 more sources

Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase

FEBS Letters, EarlyView.
The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu, Takayuki Sadakane, Yudai Murata, Junichi Taira, Hiroshi Sakamoto, Takao Kodama   +5 more
wiley   +1 more source

Molecular epidemiology and temporal dynamic of SARS-CoV-2 imported from Hong Kong to mainland China

The Microbe
Tracking the genome diversity and evolution of virus like severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was the hotspot of current researches, which were essential for the developing of prevention strategies and therapeutic vaccines.
Hai-Bo Wang, Hui-Na Huang, Xin-Bin Chen, Hai-Tang Zhou, Cheng Yuan, Jiao Ou   +5 more
doaj  

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

HIV Vaccine Research: The Challenge and the Way Forward

Journal of Immunology Research, 2015
Human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) is a worldwide epidemic, with over 35 million people infected currently. Therefore, the development of a safe and effective HIV-1 vaccine is on top of the global health priority.
Hai-Bo Wang, Qiu-Hua Mo, Ze Yang
doaj   +1 more source