Results 71 to 80 of about 1,167,337 (295)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Individual Microscopic Results Of Bottleneck Experiments

open access: yes, 2016
This contribution provides microscopic experimental study of pedestrian motion in front of the bottleneck, explains the high variance of individual travel time by the statistical analysis of trajectories.
B Steffen   +3 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

The Influence of Network Structure on Travel Distance [PDF]

open access: yes
The objective of this research is to identify the role of network architecture in influencing individual travel behavior using travel survey data from two urban areas in Florida: Fort Lauderdale and Miami.
David Levinson   +2 more
core  

Spread of infectious diseases: Effects of the treatment of population

open access: yes, 2017
In a metapopulation network, infectious diseases spread widely because of the travel of individuals. In the present study, we consider a modified metapopulation Susceptible-Infected-Removed (SIR) model with a latent period, which we call the SHIR model ...
Kudo, Kazue, Mizuno, Kanako
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Efficient Similarity Search for Travel Behavior

open access: yesIEEE Access, 2018
To provide travel recommendations and planning in the intelligent transportation system (ITS), we must have the ability to find similar travel patterns among users based on their real mobility traces.
Lei Tang   +3 more
doaj   +1 more source

CALIBRATING THE INTERCITY HIGH SPEED RAIL (HSR) CHOICE MODEL FOR THE RICHMOND-WASHINGTON, D.C. CORRIDOR [PDF]

open access: yes
This study aims to quantitatively investigate how the introduction of high-speed rail (HSR) influences traveler’s choice behavior. The study focuses on recalibrating the Florida-based HSR choice model to fit the intercity travel northward from Richmond ...
Xueming CHEN
core  

International products and purchase intention in Jordan among consumer ethnocentrism [PDF]

open access: yes, 2007
This study attempts to validate the Antecedents of Consumer Ethnocentrism and determine causal relationships between the specified antecedents and customer ethnocentrism in light of customer behavior in a less developed country Jordan.
Abbas, N. Albarq
core  

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