Results 51 to 60 of about 566,371 (309)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Metro Train Operation Plan Analysis Based on Station Travel Time Reliability
The train operation plan plays an essential role in metro systems and directly affects transportation organization efficiency and passenger service level.
Ruihua Xu, Fangsheng Wang, Feng Zhou
doaj +1 more source
A stochastic cold chain (SCC) is a common supply chain in real life that emphasizes the need for commodities to arrive fresh within time constraints. In previous research on supply chains, the time factor was regarded as a fixed number.
Thi-Phuong Nguyen +2 more
doaj +1 more source
A new measure of travel time reliability for in-vehicle navigation systems [PDF]
This article introduces a new measure of travel time reliability for implementation in the dynamic routing algorithm of an intelligent car navigation system. The measure is based on the log-normal distribution of travel time on a link and consists of two
Bell, M. G. H. +2 more
core +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Evaluation of the efficiency of congestion relief schemes on expressways has generally been based on average travel time analysis. However, road authorities are much more interested in knowing the possible impacts of improvement schemes on safety and ...
Babak MEHRAN
doaj +1 more source
This study proposes a multiobjective mixed integer nonlinear programming model for a last-mile shuttle service to improve bus commuters’ travel time reliability.
Weibin Kou +3 more
doaj +1 more source
Modelling Travel Time Reliability with the Burr Distribution
AbstractThis paper suggests the Burr distribution as a useful statistical model to represent travel time reliability through studies of the day-to-day variability in travel times on journeys in urban areas. This distribution has a flexible shape and the ability to describe the very long upper tails (and hence significant skewness) seen in observed ...
Taylor, Michael.A.P., Susilawati,
openaire +2 more sources
Valuation of travel time reliability in passenger transport [PDF]
Rietveld, P.
Tseng, Y.
core +1 more source
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source

