Results 101 to 110 of about 15,626,356 (199)

The link between travel Time Budget and Speed: a Key relationship for urban space-time dynamics [PDF]

open access: yes
The relationship between travel time budget (TTB) and speed is central to transport economics and allows us to analyze travel behaviour, urban structure and the transport system.
Iragaël Joly
core  

Do Long-Haul Travel and Jet Lag Affect Athletes’ Physiological, Humoral and Performance Outcomes? A Systematic Narrative Review

open access: yesSports
Background: Long-haul travel and jet lag can disrupt athletes’ circadian, physiological, and performance systems, potentially impairing competition outcomes.
António Benito   +7 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

A Portfolio Theory of Route Choice [PDF]

open access: yes
Although many individual route choice models have been proposed to incorporate travel time variability as a decision factor, they are typically still deterministic in the sense that the optimal strategy requires choosing one particular route that ...
Shanjiang Zhu, David Levinson
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Travel Time Budget – Decomposition of the Worldwide Mean [PDF]

open access: yes
The paper is concerned with the travel activity and more specifically the urban travel time during a day. This individual mean travel time budget (TTB) has been hypothesised by Zahavi (1980) to be a constant amount of time close to 1 hour per day.
Iragaël Joly
core  

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Heuristics and Biases in Travel Mode Choice [PDF]

open access: yes
This study applies experimental methods to analyze travel mode choice. Two different scenarios are considered. In the first scenario, subjects have to decide whether to commute by car or by metro.
Patrizia Latturolo   +2 more
core   +2 more sources

Editorial: Advances in Planning for Emerging Transportation Technologies: Towards Automation, Connectivity, and Electric Propulsion

open access: yesFrontiers in Built Environment, 2021
Samuel Labi   +5 more
doaj   +1 more source

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