Results 91 to 100 of about 99,600 (284)

Empirical evaluation of public transport travel time variability

open access: yes, 2013
Although transit travel time variability is essential for understanding the deterioration of reliability, optimising transit schedule and route choice; it has not attracted enough attention from the literature.
Kieu, Le Minh   +2 more
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Trends in commuter and leisure travel in The Netherlands 1991-2001 - Mode choice and travel time [PDF]

open access: yes
Data collected over recent years indicates that there has been an increase in the average distance of trips made, in the Netherlands (e.g. in 1985 the average trip made was 8.7 km, in 2000 the average trip length was 10.6 km (Harms, 2003)).
Christy Collins, Arianne De Blaeij
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Establishing definitions and modeling public transport travel time variability

open access: yes, 2014
Public transport travel time variability (PTTV) is essential for understanding deteriorations in the reliability of travel time, optimizing transit schedules and route choices.
Kieu, Le Minh   +2 more
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Variations in the rational use of time – The travel pulse of commutes between home and job [PDF]

open access: yes
Ian Cullen and his research colleagues long ago suggested that people form habits in daily life that suboptimize behavior in view of constraints. Such rational suboptimization is posited here to apply to trips between home and work and to vary by time of
William Michelson
core  

Exploring the Spatially Heterogeneous Effects of Urban Built Environment on Road Travel Time Variability

open access: yes, 2020
Most studies of road travel time estimation have been based on traffic-flow theory or data-driven methods and generally neglect the influence of urban built environment on road travel time.
Liu, Ao   +4 more
core   +1 more source

Uncovering the Uncertainties and Variability of Travel Time and Fuel Consumption Using Floating Car Data: A Case Study in Wuhan

open access: yesIEEE Access
Understanding the probabilistic behavior of both travel time and fuel consumption is critical for improving urban traffic efficiency and developing reliable urban transportation systems.
Wenxin Teng   +5 more
doaj   +1 more source

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