Results 81 to 90 of about 15,626,356 (199)

On Efficient "Time Travel" in Gödel Spacetime [PDF]

, 2010
Here, we show that one may "time travel" in Gödel spacetime with less total acceleration than was previously known. This answers a question posed by Malament (1985, 1986, 1987)
Manchak, John Byron, John Byron Manchak
core   +1 more source

Travel Time Variability and Spatio-Temporal Analysis of Urban Streets Using Global Positioning System: A Review

Journal of Engineering
Travel Time estimation is largely caused by the stochastic process of arrivals and departures of vehicles and its reliability measurements considering important issues for improving operational efficiency and safety for traffic road networks.
Zainab Ahmed Alkaissi, Ruba Yousif Hussain   +1 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Forecasting travel time variability [PDF]

, 2009
In order to incorporate travel time variability in appraisal, methods are needed to predict effects on travel time variability of investments and polity measures. The present study is a first step towards developing such a method.
Eliasson, Jonas
core   +2 more sources

Underground travel time estimation for macro simulation models, on the example of the first line in Warsaw

Budownictwo i Architektura, 2014
In this paper, the author’s model of underground travel time prediction was presented. The structure of the model can be used to estimate the travel time of any underground line in the planning phase.
Marek Bauer
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Trends in commuter and leisure travel in The Netherlands 1991-2001 - Mode choice and travel time [PDF]

Data collected over recent years indicates that there has been an increase in the average distance of trips made, in the Netherlands (e.g. in 1985 the average trip made was 8.7 km, in 2000 the average trip length was 10.6 km (Harms, 2003)).
Christy Collins, Arianne De Blaeij
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Impact of connected vehicle guidance information on network-wide average travel time

Advances in Mechanical Engineering, 2016
With the emergence of connected vehicle technologies, the potential positive impact of connected vehicle guidance on mobility has become a research hotspot by data exchange among vehicles, infrastructure, and mobile devices.
Jiangfeng Wang, Jiarun Lv, Qian Zhang, Xuedong Yan   +3 more
doaj   +1 more source