Results 71 to 80 of about 99,600 (284)

THE OPTIMAL DURATION FOR A TRAVEL SURVEY

IATSS Research, 2009
Empirical observations were carried out using a six-week travel survey, Mobidrive, in order to probe into the optimal duration problem of a single wave travel survey.
Metin SENBIL, Ph.D.
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The geography of inequalities in access to healthcare across England: the role of bus travel time variability

Journal of Physics: Complexity
Fair access to healthcare facilities is fundamental to achieving social equity. Traditional travel time-based accessibility measures often overlook the dynamic nature of travel times resulting from different departure times, which compromises the ...
Zihao Chen, Federico Botta
doaj   +1 more source

Using Data Mining to Analyze Dwell Time and Nonstop Running Time in Road-Based Mass Transit Systems

Proceedings, 2018
Travel Time plays a key role in the quality of service in road-based mass transit systems. In this type of mass transit systems, travel time of a public transport line is the sum of the dwell time at each bus stop and the nonstop running time between ...
Teresa Cristóbal, Gabino Padrón, Alexis Quesada, Francisco Alayón, Gabriel de Blasio, Carmelo R. García   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Forecasting travel time variability [PDF]

, 2009
In order to incorporate travel time variability in appraisal, methods are needed to predict effects on travel time variability of investments and polity measures. The present study is a first step towards developing such a method.
Eliasson, Jonas
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Variability versus stability in daily travel and activity behaviour. The case of a one week travel diary [PDF]

Temporal rhythms in travel and activity patterns are analysed thanks to a seven-day travel diary collected on 707 individuals in the city of Ghent (Belgium) in 2008.
Charles Raux, Eric Cornelis, Tai-Yu Ma
core  

Modeling Time-Varying Variability and Reliability of Freeway Travel Time Using Functional Principal Component Analysis [PDF]

, 2020
This paper presents an aproach for modeling travel time variability and reliability that accounts for time-of-day effects on travel time variations. The conditional probability density functions of travel time in each specific period play a fundamental ...
Jeng-Min Chiou ; Han-Tsung Liou; and Wan-Hui Chen
core   +1 more source