Results 201 to 210 of about 1,163,658 (291)

Personalizing Clozapine in Treatment-Resistant Schizophrenia: The Role of MicroRNA Biomarkers-A Pilot Study. [PDF]

Curr Issues Mol Biol
Sosin DN, Khasanova AK, Illarionov RA, Popova AK, Mirzaev KB, Glotov AS, Mosolov SN, Sychev DA.   +7 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Esketamine for Treatment-Resistant Depression in Pakistan: A Promising Strategy. [PDF]

Hosp Pharm
Memon M, Gul R, Gul A, Bansari S, Bansari M, Khowaja A, Kumar S, Kumar K, Khan KS, Iman K, Khan MM.   +10 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Lithium Augmentation in Treatment-Resistant Depression: A Qualitative Review of the Literature. [PDF]

Pharmacotherapy
Acero-González A, Guzman Y, Proaños NJ, Bustos RH, Aconcha M, Guerrero I, Martinez LA, Berk M, Dodd S.   +8 more
europepmc   +1 more source

Effect of body-oriented psychological therapy on negative symptoms in schizophrenia: a randomized controlled trial [PDF]

, 2006
Priebe, S, Rohricht, F
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Treatment-Resistant Atopic Dermatitis in Adulthood: A Case Report. [PDF]

Cureus
Alvarado Fernández ML, Alvarado Mora ML, Apuy Rodríguez F, Arias J, Vanegas Navarro P.   +4 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Editorial: The role of tumor microenvironment in malignant progression and target validation

Frontiers in Pharmacology
Xu Zhang, Xiyue Zhang, Weifeng Zhang, Bo Kong, Runbin Sun, Runbin Sun, Qianming Du   +6 more
doaj   +1 more source