Pragmatic randomized controlled trial of long-term psychoanalytic psychotherapy for treatment-resistant depression: the Tavistock Adult Depression Study (TADS) [PDF]
World Psychiatry, 2015 This pragmatic randomized controlled trial tested the effectiveness of long-term psychoanalytic psychotherapy (LTPP) as an adjunct to treatment-as-usual according to UK national guidelines (TAU), compared to TAU alone, in patients with long-standing ...
Andrews +49 more
core +3 more sources
Is treatment resistant depression a different subtype of depression?
European Psychiatry, 2021 Major depression is a serious, disabling, often chronic or recurrent mental disorder affecting over 350 million people worldwide. Treatment of major depression is now conceptualized as proceeding through three phases: the acute phase, the continuation ...
A. Fiorillo
doaj +1 more source
Treatment Resistant Depression [PDF]
American family physician, 2009 Up to two thirds of patients with major unipolar depression will not respond to the first medication prescribed. Depression may be considered resistant to treatment when at least two trials with antidepressants from different pharmacologic classes (adequate in dose, duration, and compliance) fail to produce a significant clinical improvement.
Philip G. Janicak, Sheila M. Dowd
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Use of pharmacotherapies for treatment resistant depression in finland: A nationwide cohort study
European Psychiatry, 2021 Introduction There is a lack of knowledge on utilized pharmacotherapies for treatment resistant depression (TRD). Objectives To investigate the courses of treatment of TRD.
H. Taipale +4 more
doaj +1 more source
Frontiers in Psychology, 2019 The current study investigated the comprehension of mindfulness-based cognitive behavioral therapy (MBCT) by patients with resistant depression at the Psychiatry Institute of the Federal University of Rio de Janeiro, Brazil.
Michele F. Rodrigues +7 more
doaj +1 more source
Accelerated intermittent theta burst stimulation for suicide risk in therapy-resistant depressed patients : a randomized, sham-controlled trial [PDF]
, 2016 Objectives: We aimed to examine the effects and safety of accelerated intermittent Theta Burst Stimulation (iTBS) on suicide risk in a group of treatment-resistant unipolar depressed patients, using an extensive suicide assessment scale.
Audenaert, Kurt +5 more
core +3 more sources
PLoS ONE, 2020 ObjectiveThe economic burden of commercially insured patients in the United States with treatment-resistant depression and patients with non-treatment-resistant major depressive disorder was compared using data from the Optum Clinformatics™ claims ...
Gang Li +7 more
doaj +2 more sources
A study of remitted and treatment-resistant depression using MMPI and including pessimism and optimism scales. [PDF]
PLoS ONE, 2014 The psychological aspects of treatment-resistant and remitted depression are not well documented.We administered the Minnesota Multiphasic Personality Inventory (MMPI) to patients with treatment-resistant depression (n = 34), remitted depression (n = 25),
Masatoshi Suzuki +5 more
doaj +1 more source
Treatment of resistant depression : a pilot study assessing the efficacy of a tDCS-mindfulness program compared with a tDCS-relaxation program [PDF]
, 2019 Background: This pilot study explores a therapeutic setting combining transcranial direct current stimulation (tDCS) and mindfulness-based cognitive therapy (MBCT) for patients with drug-resistant depression.
Campanella, Salvatore +5 more
core +2 more sources
Pharmacotherapies Targeting GABA-Glutamate Neurotransmission for Treatment-Resistant Depression
Pharmaceuticals, 2023 Treatment-resistant depression (TRD) is a term used to describe a particular type of major depressive disorder (MDD). There is no consensus about what defines TRD, with various studies describing between 1 and 4 failures of antidepressant therapies, with
Courtney M. Vecera +4 more
doaj +1 more source