Maintenance deep transcranial magnetic stimulation sessions are associated with reduced depressive relapses in patients with unipolar or bipolar depression [PDF]
Introduction: Deep transcranial magnetic stimulation (dTMS) is a new form of TMS allowing safe stimulation of deep brain regions. The objective of this preliminary study was to assess the role of dTMS maintenance sessions in protecting patients with ...
ANGELETTI, Gloria +11 more
core +2 more sources
Treatment-resistant depression and its diagnosis and treatment
The aim of this study is to explore the diagnostic strategies and options for treatment-resistant depression (TRD). Despite the well-established efficacy of antidepressants, 20%~30% of depressive patients in the clinic fail to respond or respond poorly ...
Hu Shaohua
doaj +1 more source
Antidepressant discontinuation in treatment resistant depression
Treatment-resistant depression (TRD) is a growing problem in psychiatric practice with some 15–20% of depressed patients becoming chronically depressed and perhaps as many as 40% in tertiary settings.
Ziad A. Ali +2 more
doaj +1 more source
The study protocol of the Norwegian randomized controlled trial of electroconvulsive therapy in treatment resistant depression in bipolar disorder [PDF]
Background The treatment of depressive phases of bipolar disorder is challenging. The effects of the commonly used antidepressants in bipolar depression are questionable.
Ute Kessler +7 more
core +2 more sources
Psychedelics Promote Structural and Functional Neural Plasticity. [PDF]
Atrophy of neurons in the prefrontal cortex (PFC) plays a key role in the pathophysiology of depression and related disorders. The ability to promote both structural and functional plasticity in the PFC has been hypothesized to underlie the fast ...
Barragan, Eden V +15 more
core +2 more sources
Ketamine in treatment-resistant depression
Sana Dhamija +2 more
doaj +3 more sources
Informed consent decision-making in deep brain stimulation [PDF]
Deep brain stimulation (DBS) has proved useful for several movement disorders (Parkinson’s disease, essential tremor, dystonia), in which first and/or second line pharmacological treatments were inefficacious.
Appelbaum +6 more
core +2 more sources
Case Report: Use of Subcutaneous Midazolam During an Episode of Catatonia
Midazolam is a benzodiazepine (BZD) mainly used in anesthetic induction due to its pharmacokinetic features. Its place in the therapeutic management of catatonia remains to be determined. Here we present the case of a 65-year-old man who presented with a
Valentin Raymond +5 more
doaj +1 more source
Electroconvulsive therapy mediates neuroplasticity of white matter microstructure in major depression. [PDF]
Whether plasticity of white matter (WM) microstructure relates to therapeutic response in major depressive disorder (MDD) remains uncertain. We examined diffusion tensor imaging (DTI) correlates of WM structural connectivity in patients receiving ...
Clark, K +7 more
core +1 more source
Telomere length as a predictor of response to Pioglitazone in patients with unremitted depression: a preliminary study. [PDF]
We studied peripheral leukocyte telomere length (LTL) as a predictor of antidepressant response to PPAR-γ agonist in patients with unremitted depression.
Blackburn, E +4 more
core +1 more source

