Results 61 to 70 of about 681,060 (251)

The role of the psychedelic experience in psilocybin treatment for treatment-resistant depression.

Journal of Affective Disorders
OBJECTIVE To determine the relationships between psilocybin dose, psychedelic experiences, and therapeutic outcome in treatment-resistant depression. METHODS For treatment-resistant depression, 233 participants received a single dose of 25, 10, or 1 mg
G. M. Goodwin, S. Aaronson, Oscar Alvarez, Robin Carhart-Harris, Jamie Chai-Rees, M. Croal, C. DeBattista, B. Dunlop, David Feifel, D. Hellerstein, M. I. Husain, John R. Kelly, Namik Kirlić, R. Licht, L. Marwood, Thomas D. Meyer, Sunil Mistry, A. Nowakowska, T. Páleníček, D. Repantis, R. Schoevers, H. Simmons, M. Somers, E. Teoh, J. Tsai, Mourad Wahba, S. Williams, Allan H. Young, Matthew B Young, Sidney Zisook, E. Malievskaia   +30 more
semanticscholar   +1 more source

Rapid antidepressant effects of the psychedelic ayahuasca in treatment-resistant depression: a randomized placebo-controlled trial

Psychological Medicine, 2018
Background Recent open-label trials show that psychedelics, such as ayahuasca, hold promise as fast-onset antidepressants in treatment-resistant depression.
F. Palhano-Fontes, Dayanna Barreto, H. Onias, K. Andrade, Morgana M. Novaes, J. Pessoa, S. Mota-Rolim, F. Osório, R. Sanches, R. G. dos Santos, L. F. Tófoli, Gabriela de Oliveira Silveira, M. Yonamine, J. Riba, F. Santos, Antonio A Silva-Junior, J. Alchieri, N. Galvão-Coelho, B. Lobão-Soares, J. Hallak, Emerson Arcoverde, J. P. Maia-de-Oliveira, D. Araujo   +22 more
semanticscholar   +1 more source

Magnitude of the Placebo Response Across Treatment Modalities Used for Treatment-Resistant Depression in Adults

JAMA Network Open, 2021
Key Points Question What is the placebo effect magnitude in different treatment modalities used for management of patients with treatment-resistant depression? Findings In this systematic review and meta-analysis of 3228 patients with treatment-resistant
Brett D. M. Jones, L. Razza, C. Weissman, Jewel Karbi, Tya Vine, Louise S. Mulsant, A. Brunoni, M. Husain, B. Mulsant, D. Blumberger, Z. Daskalakis   +10 more
semanticscholar   +1 more source

Moderators of the Effects of Exercise and Manual Therapy for People With Knee and Hip Osteoarthritis: A Secondary Analysis of a Randomized Clinical Trial

Arthritis Care &Research, EarlyView.
Objective This study aimed to investigate potential moderators influencing the effects of manual therapy and exercise therapy on pain and functional outcomes in individuals with knee and/or hip osteoarthritis, using data from the MOA trial. This is a secondary analysis of data from the MOA trial that compares the clinical effectiveness of manual ...
Daniel Cury Ribeiro, Sarah E. Lamb, J. Haxby Abbott   +2 more
wiley   +1 more source

Comparative effectiveness research trial for antidepressant incomplete and non-responders with treatment resistant depression (ASCERTAIN-TRD) a randomized clinical trial

Molecular Psychiatry
Further research is needed to help improve both the standard of care and the outcome for patients with treatment-resistant depression. A particularly critical evidence gap exists with respect to whether pharmacological or non-pharmacological augmentation
G. Papakostas, Madhukar H. Trivedi, R. Shelton, D. Iosifescu, Michael E. Thase, Manish K. Jha, S. J. Mathew, C. DeBattista, Mehmet e Dokucu, Olga Brawman-Mintzer, Glenn W. Currier, W. V. McCall, M. Modirrousta, Matthew Macaluso, A. Bystritsky, Fidel Vila Rodriguez, Erik B. Nelson, A. Yeung, Anna Feeney, Leslie C. MacGregor, Thomas J. Carmody, M. Fava   +21 more
semanticscholar   +1 more source

Integrating Patient‐Reported Quality Measures in Systemic Lupus Erythematosus: Development of the American College of Rheumatology Implementation Guide

Arthritis Care &Research, EarlyView.
Objective To support high‐quality, patient‐centered care for systemic lupus erythematosus (SLE), the American College of Rheumatology (ACR) developed evidence‐based measures incorporating clinical and patient‐reported outcome measures (PROMs). Using the Consolidated Framework for Implementation Research (CFIR), we conducted semistructured interviews ...
Catherine Nasrallah, Cherish Wilson, Christine Hariz, Christie M. Bartels, Shanthini Kasturi, Wambui Machua, Amy Bennett, Kate Chiseri, Allison Plitman, Starla Hairston Blanks, April Jorge, Patti Katz, Jinoos Yazdany, Shivani Garg   +13 more
wiley   +1 more source

Clinical and biological markers of electroconvulsive therapy effectiveness: a narrative review

Translational Psychiatry
Electroconvulsive therapy (ECT) is the most effective treatment for several particularly severe or pharmacotherapy-resistant psychiatric disorders, and a growing number of studies have investigated factors influencing the effectiveness of ECT.
David Zilles-Wegner, Iven-Alex von Mücke-Heim, Antoine Yrondi, Akihiro Takamiya   +3 more
doaj   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Esketamine Nasal Spray Plus Oral Antidepressant in Patients With Treatment-Resistant Depression: Assessment of Long-Term Safety in a Phase 3, Open-Label Study (SUSTAIN-2).

Journal of Clinical Psychiatry, 2020
OBJECTIVE To evaluate long-term safety and efficacy of esketamine nasal spray plus a new oral antidepressant (OAD) in patients with treatment-resistant depression (TRD).
E. Wajs, L. Aluisio, R. Holder, E. Daly, R. Lane, P. Lim, Joyce E George, R. Morrison, G. Sanacora, A. Young, S. Kasper, A. Sulaiman, Cheng-Ta Li, J. Paik, H. Manji, D. Hough, Jennifer Grunfeld, H. Jeon, S. Wilkinson, W. Drevets, Jaskaran Singh   +20 more
semanticscholar   +1 more source

The Multiple Facets of Treatment-Resistant Depression [PDF]

CNS Spectrums, 2004
info:eu-repo/semantics ...
Souery, Daniel, Der Auwera, Karel Van
openaire   +3 more sources