Results 161 to 170 of about 59,572 (271)

Association between initial 30‐day cumulative clozapine dose and risk of agranulocytosis: A nationwide register‐based cohort study

Psychiatry and Clinical Neurosciences, EarlyView.
Aims Clozapine‐induced agranulocytosis (CIA) is traditionally considered an idiosyncratic, dose‐independent reaction. However, emerging evidence suggests that clozapine‐related inflammatory events may exhibit dose‐dependent characteristics, leading us to hypothesize that CIA risk may similarly relate to early cumulative exposure.
Yuki Kikuchi, Xue Li, Hiroshi Komatsu, Norio Yasui‐Furukori, Ken Inada, Hiroaki Tomita   +5 more
wiley   +1 more source

Characterizing social motivation deficits in treatment‐resistant schizophrenia: Evidence from social incentive performance

Psychiatry and Clinical Neurosciences, EarlyView.
Aim The Treatment‐Response‐and‐Resistance‐in‐Psychosis (TRRIP) criteria recognizes negative symptoms as defining features for treatment‐resistant schizophrenia (TRS). Social motivation refers to the desire to pursue social reward (and to avoid social punishment).
Simon S.Y. Lui, Jasmine W.S. Chan, Jason L.F. Chan, Kimi H.Y. Lam, Lok‐Yin Choi, Raisie W.K. Wong, Perry B.M. Leung, Na Zhan, Jason W.Y. Wong, Mindi W.Y. Chiu, Jenny P.H. Lam, Raymond C.K. Chan   +11 more
wiley   +1 more source

Influence of 5-HT1A and 5-HTTLPR genetic variants on the schizophrenia symptoms and occurrence of treatment-resistant schizophrenia

, 2015
Tea Terzić,1 Matej Kastelic,2 Vita Dolžan,2 Blanka Kores Plesničar11Ljubljana University Psychiatric Hospital, Ljubljana, Slovenia; 2Pharmacogenetics Laboratory, Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, Ljubljana ...
Terzić T, Dolžan V, Plesničar BK, Kastelic M   +3 more
core  

When Regulation Travels: Distrust and Disrespect

Regulation &Governance, EarlyView.
ABSTRACT Endeavoring to avoid the pitfalls of being too trusting of regulated entities' compliance claims, regulators sometimes create regulatory systems with elaborate requirements for verification. But as these accountability and verification regimes attempt to circumvent one set of problems, they may inadvertently create others.
Carol A. Heimer
wiley   +1 more source

Toward a comprehensive method of phenomenological understanding: Foucault’s early critique of Jaspers’s “hermeneutic limit”

The Southern Journal of Philosophy, EarlyView.
Abstract In this article, I highlight the significant influence that Karl Jaspers had on the early Foucault. In particular, I focus on what I refer to as the “hermeneutic limit” of Jaspers's phenomenologically inspired method of intuitive understanding.
Leonhard Riep
wiley   +1 more source

Clozapine for treatment-resistant schizophrenia with epilepsy: A case report. [PDF]

PCN Rep
Horinouchi T, Mito M, Ishikawa T, Nakamura Y, Ishikawa S, Hashimoto N.   +5 more
europepmc   +1 more source

Inference and Imagination

Topics in Cognitive Science, EarlyView.
Abstract Our ability to imagine alternatives to reality is central to everyday cognition. Our competence in reasoning depends not only on our capacity to envisage the relevant facts, but also on our proficiency in simulating alternatives to them. I discuss how our skill in making deductive inferences depends on imagining possibilities. To illustrate, I
Ruth M. J. Byrne
wiley   +1 more source

A scoping review of genetic studies of treatment-resistant schizophrenia. [PDF]

Front Genet
Das U, Riel H, Enriquez MR, Shirinbakhshmasoleh M, Rose A, Herrera M, Lu Y, Kowalec K.   +7 more
europepmc   +1 more source

The cardiac pacemakers: A paradigm of robustness in evolutionary biology

The Journal of Physiology, EarlyView.
Abstract figure legend Functional networks in living systems are formed by many thousands of gene products. In association with those networks, several genes (four in this diagram) may be sufficient, each on its own, to ensure that the function occurs. Any one of these may be removed or blocked while leaving the others to continue functioning.
Denis Noble
wiley   +1 more source

A Real‐World Pilot of the Collaborative Care Model for Adults With Cognitive Impairment and Neuropsychiatric Symptoms in Primary Care

Psychiatric Research and Clinical Practice, EarlyView.
Objective The Collaborative Care Model, which integrates primary care, behavioral health, and structured care management, is a promising approach to improving outcomes for patients with cognitive impairment and neuropsychiatric symptoms. This study evaluated a pilot of Cognitive Impairment Collaborative Care (CICC) at a large urban academic medical ...
Daniel Y. Johnson, Erin M. Staab, Peter Hahn, Carly Lusk, Erin K. Zahradnik, Neda Laiteerapong   +5 more
wiley   +1 more source