Results 91 to 100 of about 35,714,339 (381)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Surgical outcome of endoscopic endonasal approach as a modality of management for large and giant pituitary adenomas: a retrospective case series

Egyptian Journal of Neurosurgery
Background Large and giant pituitary adenomas (defined as tumors of maximal diameter ≥ 3–3.9 cm and ≥ 4 cm, respectively) present considerable surgical challenges regarding the extent of resection and perioperative morbidity.
Shebl Izz-alarab, Michael Zohney, Saied A. Issa, Abdelaleem Abdelwahab, Ashraf G. Al-Abyad, Mohamed M. Aziz   +5 more
doaj   +1 more source

Application efficiency and effectiveness of Botulinum neurotoxin type A in complex treatment of patients with post – stroke spasticity in arm

Анналы клинической и экспериментальной неврологии, 2017
Studying of efficiency of application botulinum neurotoxin type Ain complex treatment 51 patients with poststroke spastic hemiparesiswith mean time from stroke onset 33.8 months.
E. S. Koneva, E. S. Khatkova, A. V. Albegova, I. V. Sidyakina, M. R. Makarova, T. V. Shapovalenko, K. V. Lyadov   +6 more
doaj   +1 more source

Vector diseases treatment based on intermediate complexion using textile substrates [PDF]

, 2019
The most efficient insect repellents are DEET (N, N-diethhyl-meta-toluamide) from synthetic origin and citronella essential oil from natural origin. However, there are other products that can also be used as insect repellents from synthetic origin, such ...
Lis Arias, Manuel José, Maesta Bezerra, Fabricio, Silva, Tais Larissa   +2 more
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Effects of financial support on treatment of adolescents with growth hormone deficiency: a retrospective study in Japan

BMC Health Services Research, 2016
Background Treatment costs for children with growth hormone (GH) deficiency are subsidized by the government in Japan if the children meet clinical criteria, including height limits (boys: 156.4 cm; girls: 145.4 cm).
Eri Maeda, Takahiro Higashi, Tomonobu Hasegawa, Susumu Yokoya, Takahiro Mochizuki, Tomohiro Ishii, Junko Ito, Susumu Kanzaki, Akira Shimatsu, Koji Takano, Toshihiro Tajima, Hiroyuki Tanaka, Yusuke Tanahashi, Akira Teramoto, Toshiro Nagai, Kunihiko Hanew, Reiko Horikawa, Toru Yorifuji, Naohiro Wada, Toshiaki Tanaka   +19 more
doaj   +1 more source

2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure.

European Heart Journal, 2021
T. McDonagh, M. Metra, M. Adamo, R. S. Gardner, A. Baumbach, Michael Böhm, H. Burri, J. Butler, J. Čelutkienė, O. Chioncel, John G. Cleland, A. Coats, M. Crespo-Leiro, Dimitrios Farmakis, Martine Gilard, Stephane Heymans, Arno W. Hoes, T. Jaarsma, E. A. Jankowska, M. Lainščak, C. S. Lam, A. Lyon, J. J. McMurray, A. Mebazaa, Richard Mindham, Claudio Muneretto, Massimo Francesco Piepoli, Susanna Price, G. Rosano, F. Ruschitzka, Anne Kathrine Skibelund   +30 more
semanticscholar   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source