Results 111 to 120 of about 15,557,216 (297)

Does acute-phase acupuncture at Hegu (LI04) promote facial nerve regeneration and upregulation of the PI3K/Akt/mTOR pathway? A hypothesis-generating study in a rabbit crush injury model

open access: yesFrontiers in Neurology
This study used the rabbit facial nerve crush injury model to investigate the time-dependent effects of acupuncture at Hegu (LI04) on facial nerve regeneration and regulatory role of the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt ...
Jin Song   +8 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Prerequisites for incorporating groundwater assimilative capacity as a legitimate treatment component of a land based waste treatment system

open access: yes, 2014
Nitrogen assimilation processes that occur when effluent is applied onto a land based waste treatment (LBWT) site are not necessarily restricted to the root zone.
Barkle, G, Stenger, R
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Fargo Water Treatment Plant Records, 1911-1993 [PDF]

open access: yes, 2008
Records detailing the daily operation of one of the nation's earliest water treatment ...
Fargo Water Treatment Plant
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Sex offender treatment providers: registry.

open access: yes, 1993
Directory of mental health professionals in Texas who meet the minimum requirements for training and experience regarding knowledge and experience with the sex offender ...
Texas. Council on Sex Offender Treatment.
core  

Pharmacological Treatment of Schizophrenia

open access: yes, 2023
Schizophrenia is a complex psychiatric disorder, characterized by symptoms such as delusions, hallucinations, disordered thinking, and behavior that affect a person's ability to function normally.
Goldstein, Tom
core  

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