Results 151 to 160 of about 15,557,216 (297)

Cost-Effectiveness of Reducing HIV Infections Through Screening and Treating Alcohol Use and Depression in KwaZulu-Natal, South Africa: A Mathematical Modeling Study. [PDF]

open access: yesJ Acquir Immune Defic Syndr
Jeetoo M   +10 more
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Treatment review guidelines

open access: yes, 2006
Drug Treatment Centre Board (Ireland ...
Drug Treatment Centre Board (DTCB)
core  

Management of Neuropathic Pain in Complex Regional Pain Syndrome: A Comprehensive Review. [PDF]

open access: yesPain Pract
Donati D   +5 more
europepmc   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

A report on the patient treatment register [PDF]

open access: yes, 2008
National Treatment Purchase Fund
core  

Treatment of Idiopathic Thrombocytopenic Purpura

open access: yes, 2018
Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disorder characterized by low number of platelet counts. ITP causes by increased platelet destruction and insufficient platelet production.
Nguyen, Thuong Huy
core  

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