Results 161 to 170 of about 13,587,543 (295)

PER1 Serves as a Tumor Suppressor in Breast Cancer by Regulating MEK5/ERK5 Signaling Pathway

open access: yesInternational Journal of General Medicine
Yinfeng Liu,1 Dandan Yang,2 Zihang Xu,1 Ji Lv,1 Zizheng Wu,1 Jie Zheng,1,3 Meng Han,1 Guanli Yuan4 1Breast Disease Diagnosis and Treatment Center, The First Hospital of Qinhuangdao, Qinhuangdao, Hebei, People’s Republic of China; 2Clinical Laboratory ...
Liu Y   +7 more
doaj  

Physicochemical methods for water and wastewater treatment proceedings of the second international conference, Lublin, June 1979

open access: yes, 1980
Physicochemical Methods for Water and Wastewater Treatment covers the proceedings of the Second International Conference held in Lublin in June 1979. The papers in this compendium discuss scientific findings on how to treat water and wastewater using ...
International Conference on Physicochemical Methods for Water and Wastewater Treatment < 1979, Lublin, Poland>   +1 more
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Combining Treatment of Acute Malnutrition With Integrated Community Case Management: A Cluster-Randomised Controlled Trial (SETiPlus). [PDF]

open access: yesMatern Child Nutr
Cronin G   +11 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Swedish Intensive Care Physicians' Attitudes Towards Withholding or Withdrawing Life-Sustaining Treatment in Critically Ill Children. [PDF]

open access: yesActa Anaesthesiol Scand
Ahlerup M   +7 more
europepmc   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Vunakizumab for IL-17A&ndash;Mediated Diseases: A Review in Psoriasis and Spondyloarthritis

open access: yesBiologics: Targets & Therapy
Hongzhuo Yan,1,2,&ast; Yu Chen,3,&ast; Yali Song,1 Min Yan,1 Kexiang Yan1 1Dermatology Diagnosis and Treatment Center, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2Shanghai
Yan H, Chen Y, Song Y, Yan M, Yan K
doaj  

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