Results 61 to 70 of about 7,725,061 (294)

PROBLEMS IN THE PHYSICIAN-PATIENT DYAD

Туберкулез и болезни лёгких, 2014
Phthisiatrician-patient cooperation, the efficiency of which largely depends is influenced by the outcome of treatment, is one of the aspects of antituberculosis therapy.
T. V. Pyanzova
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Adherence to treatment guidelines in a university hospital: Exploration of facts and factors

Bangladesh Journal of Pharmacology, 2014
The present study was conducted to evaluate the adherence to treatment guidelines in Bangabandhu Sheikh Mujib Medical University. The study assessed the awareness of prescribers, adherence to treatment guidelines and reasons for non-adherence.
Swarmita Afreen, Md. Sayedur Rahman
doaj  

APPROACHES TO STATIN THERAPY ADHERENCE IMPROVEMENT

Кардиоваскулярная терапия и профилактика, 2018
Most cardiovascular diseases (CVD) are of atherosclerotic origin, and lipid disorders play significant role, setting up the cardiovascular continuum, together with other risk factors.
S. A. Shalnova, V. N. Belov, M. N. Valiakhmetov, N. G. Veselovskaya, N. V. Voronina, A. V. Dmitriev, E. V. Efremova, L. О. Minushkina, A. М. Naydich, V. Yu. Pavlova, Ya. M. Pakhomov, A. Е. Rivin, L. I. Feiskhanova, Е. V. Khorolets, О. P. Askerko, E. Z. Topuridze   +15 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Problem of treatment adherence in tuberculosis patients

Туберкулез и болезни лёгких, 2015
Tuberculosis is one of the most dangerous social and medical problems. Despite the relative stabilization of some tuberculosis epidemiological rates in general tuberculosis situation remains to be difficult.
A. V. Belostotsky, T. Ch. Kasaeva, N. V. Kuzmina, N. V. Nelidov   +3 more
doaj  

Analysis of factors affecting tuberculosis treatment adherence at Lesung Batu Community Health Center: A cross-sectional study

Lentera Perawat
Background Tuberculosis (TB) remains a major global health problem with high rates of morbidity and mortality, particularly in developing countries like Indonesia.
Puspita Kurnia Sari, Ali Harokan, Lilis Suryani   +2 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Access to art, adherence and drug resistance among HIV-Positive patients in rural Tanzania [PDF]

, 2015
HIV is one of the worst pandemics in recent times, having affected more than 70 million and with a mortality rate close to 50%. Antiretroviral drugs fight viral replication and has improved life of HIV infected patients since it was introduced.
Nyogea, Daniel, Nyogea, Daniel Simon
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source