Results 121 to 130 of about 4,239,487 (340)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Total ventricular assist for long-term treatment of heart failure [PDF]

, 2011
Antoniοs Pitsis, Aikaterini N. Visouli, Vlasis Ninios, Dimitrios Th. Kremastinos   +3 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Clinical characteristics and quality assessment of the treatment of patients with chronic heart failure with diabetes mellitus

, 2020
N. Lazareva, Е. В. Ощепкова, А. A. Orlovsky, S. N. Тereschenko   +3 more
openalex   +2 more sources

Abstract No. 537 Failure rates of pulse versus continuous fluoroscopy for the treatment of benign prostatic hyperplasia via prostatic artery embolization [PDF]

, 2021
S. Momin, Adarsh Dharan, Seema Rao
openalex   +1 more source

Treatment Rate Of Second Mesio-Buccal Canals In Maxillary Molars In A Musod Endodontic Resident Patient Population [PDF]

, 2013
Purpose: The primary reason for non-surgical root canal treatment (NSRCT) failure in an upper molar is inadequate cleaning, shaping and filling of the second mesio-buccal root canal (MB2). Failure to locate and treat a present MB2 will lead to a worsened
Margel, Ryan Yale
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Outcomes and readmissions after cardiac surgery in patients with chronic steroid use: a nationwide propensity score matched analysis

Journal of Cardiothoracic Surgery
Background We characterized index admission outcomes and 30-day readmissions after cardiac surgery in patients with chronic steroid use (CSU) in a large national administrative database.
Jean-Luc A. Maigrot, Guangjin Zhou, Siran M. Koroukian, Nicholas Schiltz, Edward G. Soltesz   +4 more
doaj   +1 more source

POS0057 WHICH ADVANCED TREATMENT SHOULD BE USED FOLLOWING THE FAILURE OF A FIRST-LINE ANTI-TNF IN PATIENTS WITH RHEUMATOID ARTHRITIS? 15 YEARS OF EVIDENCE FROM THE QUEBEC REGISTRY RHUMADATA™ [PDF]

, 2023
D. Choquette, Louis Bessette, Loïc Choquette Sauvageau, James A. Brown, Isabelle Ferdinand, Paul Haraoui, Maxine Joly-Chevrier, Ariel Masetto, Frédéric Massicotte, V. Nadon, J.-P. Pelletier, J. P. Raynauld, D. Sauvageau, A. Turcotte, Édith Villeneuve, Louis Coupal   +15 more
openalex   +1 more source