Results 181 to 190 of about 4,239,487 (340)

Increased modified DUBLIN scores are associated with serious ulcerative colitis and treatment failure

, 2022
Lupeng Liu, Hui Ouyang, Jingling Su, Yumei Lin, Yiqun Hu, Huaxiu Shi, Chenxi Xie   +6 more
openalex   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Conservative Treatment of Spondylodiscitis: Possible Therapeutic Solution in Case of Failure of Standard Therapy

, 2019
Enrico Maria Bonura, David L.S. Morales, Domenico Fenga, Giuseppe Rollo, Luigi Meccariello, Danilo Leonetti, Francesco Traina, Francesco Centofanti, Rosa Ma   +8 more
openalex   +2 more sources

Clinical analysis of fixation failure in the treatment of intertro chanteric fracture of the femur [PDF]

, 1991
Jong Deuk Rha, Young Hoon Kim, Sung Il Yoon, Jun Soon Kang, Duck Hyun Park   +4 more
openalex   +1 more source

S177: JAK INHIBITION AND COMBINATION THERAPY IN THE TREATMENT OF MURINE BONE MARROW FAILURE

, 2023
Xingmin Feng, Jibran Durrani, Ash Lee Manley, Wu Zhi, Nidhi Aggarwal, Jichun Chen, Emma M. Groarke, Young Neal   +7 more
openalex   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Probabilistic classification of late treatment failure in uncomplicated falciparum malaria. [PDF]

Nat Commun
Mehra S, Taylor AR, Imwong M, White NJ, Watson JA.   +4 more
europepmc   +1 more source

Endovascular Rescue Treatment for Occlusion of Renal Arteries Resulting in Acute Renal Failure

, 2018
Paweł Latacz, Marian Simka, Marcin Krzanowski, Joanna Dolipska, Władysław Sułowicz, D Silverberg, T Menes, U Rimon, P Latacz, A Rudnik, A Gutowska, H Kanamori, M Toma, A Fukatsu, N Hedayati, P Lin, A Lumsden, V Jongkind, J Kievit, A Wiersema, P Latacz, M Simka, M Krzanowski, Pawe Latacz, Marian Simka, Marcin Krzanowski, Joanna Dolipska, Wadysaw Suowicz   +27 more
openalex   +1 more source