Results 211 to 220 of about 4,239,487 (340)

New perspectives in the definition and classification of acute-on-chronic liver failure

Chinese Medical Journal
Manman Xu, Yu Chen, Yanjie Yin
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Cutaneous Angiosarcoma Mimicking Masson's Tumor in an Elderly Male: A Diagnostic Challenge and Treatment Failure. [PDF]

Cureus
Alzaabi M, Alroumi A, Al-Sabah H.
europepmc   +1 more source

Six-month freedom from treatment failure is an important end point for acute GVHD clinical trials

, 2013
Salyka Sengsayadeth, Bipin N. Savani, Madan Jagasia, S. Goodman, John P. Greer, Heidi Chen, Wichai Chinratanalab, Adetola A. Kassim, Brian G. Engelhardt   +8 more
openalex   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Treating Multiline Treatment Failure in Advanced Colon Cancer Based on Evolutionary Theory: A Case Report. [PDF]

Int Med Case Rep J
Wu X, Xian Q, Ling R, Zhu W.
europepmc   +1 more source

COVID‐19 Patients Have Peripheral Microvascular Dysfunction and Tissue Hypoxia in Spite of Successful Treatment of Lung Failure: A Proof of Concept Study [PDF]

Knut Kvernebo, L. Liv Kristin Wikslund, Kamila Drezek, Andrea Jaramillo, Luigino Capone, Maged Helmy, Yunong Zhao, Aaron D. Aguirre, David D’Alessandro   +8 more
openalex   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Treatment failure of over-the-counter pediculicide shampoos in Thai schoolgirls: Evidence of insecticide resistance. [PDF]

Parasitol Res
Thanchomnang T, Krittanan P, Yangthaworn K, Yingklang M.   +3 more
europepmc   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source