Results 41 to 50 of about 4,239,487 (340)

Psoas Muscle Index Can Be Used to Predict Long-Term Mortality in Young Male Patients With Acute-on-Chronic Liver Failure

Frontiers in Nutrition, 2022
ObjectiveThe use of psoas muscle index (PMI) in acute-on-chronic liver failure (ACLF) has not been reported, and the aim of this study was to evaluate the predictive value of PMI for the prognosis of patients with ACLF.MethodsIn this study, male ACLF ...
Manman Xu, Manman Xu, Tongzeng Li, Ming Kong, Ming Kong, Nan Geng, Nan Geng, Wenyan Song, Guanya Guo, Zhongping Duan, Zhongping Duan, Ying Han, Yu Chen, Yu Chen   +13 more
doaj   +1 more source

Estimating the causal effect of a time-varying treatment on time-to-event using structural nested failure time models

, 2003
In this paper we review an approach to estimating the causal effect of a time-varying treatment on time to some event of interest. This approach is designed for the situation where the treatment may have been repeatedly adapted to patient characteristics,
Dawid A. P., Gill R. D., Lok J. J., Robins J. M., Robins J. M., Robins J. M., Robins J. M., Robins J. M., Robins J. M., Robins J. M., Rubin D. B., Van der Laan M. J., Van der Vaart A. W.   +12 more
core   +4 more sources

Efficacy of sulfadoxine-pyrimethamine in Tanzania after two years as first-line drug for uncomplicated malaria: assessment protocol and implication for treatment policy strategies. [PDF]

, 2005
BACKGROUND\ud \ud Systematic surveillance for resistant malaria shows high level of resistance of Plasmodium falciparum to sulfadoxine-pyrimethamine (SP) across eastern and southern parts of Africa. This study assessed in vivo SP efficacy after two years
Abdulla, Salim, Beck, Hans-Peter, Falk, Nicole, Felger, Ingrid, Genton, Blaise, Masanja, Honorati, Mshinda, Hassan, Mugittu, Kefas   +7 more
core   +3 more sources

Are there etiology-specific risk factors for adverse outcomes in patients on Impella 5.5 support?Central MessagePerspective

JTCVS Open
Objectives: To identify possible etiology-specific differences in preoperative risk factors for major adverse events during Impella 5.5 support in patients with ischemic (ICM) and nonischemic cardiomyopathy (NICM).
Jean-Luc A. Maigrot, BS, Lucy Thuita, MS, Michael Z.Y. Tong, MD, MBA, Edward G. Soltesz, MD, MPH, Nicholas G. Smedira, MD, MBA, Shinya Unai, MD, Randall C. Starling, MD, MPH, Andrew Higgins, MD, David Moros, MD, Eugene H. Blackstone, MD, Aaron J. Weiss, MD, PhD   +10 more
doaj   +1 more source

Increased INR Values Predict Accelerating Deterioration and High Short-Term Mortality Among Patients Hospitalized With Cirrhosis or Advanced Fibrosis

Frontiers in Medicine, 2021
Background and Objective: An increase in the international normalized ratio (INR) is associated with increased mortality in patients with cirrhosis and other chronic liver diseases, while little is known about the quantitative relationship.
Ying Wang, Ying Wang, Fuchen Dong, Fuchen Dong, Shuning Sun, Shuning Sun, Xianbo Wang, Xianbo Wang, Xin Zheng, Xin Zheng, Yan Huang, Yan Huang, Beiling Li, Beiling Li, Yanhang Gao, Yanhang Gao, Zhiping Qian, Zhiping Qian, Feng Liu, Feng Liu, Xiaobo Lu, Xiaobo Lu, Junping Liu, Junping Liu, Haotang Ren, Haotang Ren, Yubao Zheng, Yubao Zheng, Huadong Yan, Huadong Yan, Guohong Deng, Guohong Deng, Liang Qiao, Liang Qiao, Yan Zhang, Yan Zhang, Wenyi Gu, Wenyi Gu, Xiaomei Xiang, Xiaomei Xiang, Yi Zhou, Yi Zhou, Baoyan Xu, Baoyan Xu, Yixin Hou, Yixin Hou, Qun Zhang, Qun Zhang, Yan Xiong, Yan Xiong, Congcong Zou, Congcong Zou, Jun Chen, Jun Chen, Zebing Huang, Zebing Huang, Xiuhua Jiang, Xiuhua Jiang, Tingting Qi, Tingting Qi, Sen Luo, Sen Luo, Yuanyuan Chen, Yuanyuan Chen, Na Gao, Na Gao, Chunyan Liu, Chunyan Liu, Wei Yuan, Wei Yuan, Xue Mei, Xue Mei, Jing Li, Jing Li, Tao Li, Tao Li, Rongjiong Zheng, Rongjiong Zheng, Xinyi Zhou, Xinyi Zhou, Weituo Zhang, Weituo Zhang, Hai Li, Hai Li, Zhongji Meng, Zhongji Meng   +85 more
doaj   +1 more source

Kuhuang injection exerts a protective effect by activating PPAR-γ in an in vitro model of chlorpromazine-induced cholestatic liver injury constructed by tissue engineering

Pharmaceutical Biology, 2022
Context Kuhuang (KH) injection is a widely used anticholestatic drug in the clinic and the mechanisms are still unclear.Objective This study uses a new 3D tissue-engineered (TE) liver platform to study the ability of kuhuang to ameliorate liver injury ...
Qiao Wu, Zhongping Duan, Long Huang, Zhijie Li   +3 more
doaj   +1 more source

Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin in acute lung injury to reduce pulmonary dysfunction (HARP-2) trial : study protocol for a randomized controlled trial [PDF]

, 2012
Acute lung injury (ALI) is a common devastating clinical syndrome characterized by life-threatening respiratory failure requiring mechanical ventilation and multiple organ failure.
A Mercat, AM Cheung, C Brun-Buisson, C Rossi, Cecilia M O’Kane, Christine McNally, Daniel F McAuley, DJ Kor, Excellence NIfHaC, F Gao Smith, Gavin D Perkins, GD Rubenfeld, GR Bernard, Grainne Crealey, Irish Critical Care Trials Group, John G Laffey, KF Schulz, LA Curtis, Lynn Murphy, M Shyamsundar, MA Matthay, Mark Cross, Michael Stevenson, MS Herridge, RG Brower, S Harvey, SE Erickson, T Craig, The ARDS Network investigators, The EuroQol Group, TR Craig, TW Felton   +31 more
core   +1 more source

The MedSupport Multilevel Intervention to Enhance Support for Pediatric Medication Adherence: Development and Feasibility Testing

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction We developed MedSupport, a multilevel medication adherence intervention designed to address root barriers to medication adherence. This study sought to explore the feasibility and acceptability of the MedSupport intervention strategies to support a future full‐scale randomized controlled trial.
Elizabeth G. Bouchard, Hital Patel, Paula C. Vincent, Justine Kahn, Kira Bona, Thai Hoa Tran, Elisa M. Rodriguez, Kristopher Attwood, Kara M. Kelly   +8 more
wiley   +1 more source

Reduction of transmission from malaria patients by artemisinin combination therapies: a pooled analysis of six randomized trials. [PDF]

, 2008
BACKGROUND: Artemisinin combination therapies (ACT), which are increasingly being introduced for treatment of Plasmodium falciparum malaria, are more effective against sexual stage parasites (gametocytes) than previous first-line antimalarials and ...
Bousema, Teun, Drakeley, Chris J, Ghani, Azra C, Okell, Lucy C, Sutherland, Colin J   +4 more
core   +3 more sources

Management of early pregnancy loss with mifepristone and misoprostol: clinical predictors of treatment success from a randomized trial. [PDF]

, 2020
BackgroundEarly pregnancy loss is a common event in the first trimester, occurring in 15%-20% of confirmed pregnancies. A common evidence-based medical regimen for early pregnancy loss uses misoprostol, a prostaglandin E1 analog, with a dosage of 800 μg,
Atrio, Jessica M, Creinin, Mitchell D, Koelper, Nathanael, McAllister, Arden, Sammel, Mary D, Schreiber, Courtney A, Sonalkar, Sarita   +6 more
core   +1 more source