Results 51 to 60 of about 252,808 (266)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Weekly irinotecan in a patient with metastatic colorectal cancer on hemodialysis due to chronic renal failure [PDF]

, 2002
Background: The cytotoxic treatment of patients suffering from advanced or metastatic cancer undergoing hemodialysis due to chronic renal failure still remains a problem, since for those patients pharmacokinetic and pharmacodynamic data on most cytotoxic
Stemmler, J., Hacker, U., Schalhorn, A., Weise, A., Heinemann, Volker   +4 more
core   +1 more source

Kuhuang injection exerts a protective effect by activating PPAR-γ in an in vitro model of chlorpromazine-induced cholestatic liver injury constructed by tissue engineering

Pharmaceutical Biology, 2022
Context Kuhuang (KH) injection is a widely used anticholestatic drug in the clinic and the mechanisms are still unclear.Objective This study uses a new 3D tissue-engineered (TE) liver platform to study the ability of kuhuang to ameliorate liver injury ...
Qiao Wu, Zhongping Duan, Long Huang, Zhijie Li   +3 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The COACH risk engine: a multistate model for predicting survival and hospitalization in patients with heart failure [PDF]

, 2012
Aims: Several models for predicting the prognosis of heart failure (HF) patients have been developed, but all of them focus on a single outcome variable, such as all-cause mortality.
Postmus, Douwe; id_orcid, Buskens, Erik; id_orcid, Harjola, Veli-Pekka,, Lewsey, James, Postmus, D., Postmus, Douwe, Hans L. Hillege, Lassus, Johan,, Hillege, Hans L.,, James Lewsey, Luttik, Marie Louise, van Veldhuisen, Dirk J.,, Harjola, V.P., Hillege, Hans L., Nieminen, M.S., Lewsey, James,, Mebazaa, Alexandre,, Veli‐Pekka Harjola, van Veldhuisen, Dirk J., Harjola, Veli-Pekka, Markku S. Nieminen, Buskens, Erik,, Luttik, Marie Louise,, Jaarsma, Tiny,, Alexandre Mebazaa, Buskens, E., Douwe Postmus, van Veldhuisen, D.J., Hillege, H.L., Johan Lassus, Buskens, Erik, Erik Buskens, Postmus, Douwe,, Marie Louise Luttik, Nieminen, Markku S., Lassus, J., Mebazaa, A., Jaarsma, Tiny, Jaarsma, T., Lassus, Johan, Dirk J. van Veldhuisen, Nieminen, Markku S.,, Luttik, M.L., Tiny Jaarsma, Lewsey, J., Mebazaa, Alexandre   +45 more
core   +1 more source

A dynamic prediction model for prognosis of acute-on-chronic liver failure based on the trend of clinical indicators

Scientific Reports, 2021
Acute-on-chronic liver failure (ACLF) is a dynamic syndrome, and sequential assessments can reflect its prognosis more accurately. Our aim was to build and validate a new scoring system to predict short-term prognosis using baseline and dynamic data in ...
Zhenjun Yu, Yu Zhang, Yingying Cao, Manman Xu, Shaoli You, Yu Chen, Bing Zhu, Ming Kong, Fangjiao Song, Shaojie Xin, Zhongping Duan, Tao Han   +11 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The EuroHeart Failure survey programme—a survey on the quality of care among patients with heart failure in Europe Part 1: patient characteristics and diagnosis

, 2003
The European Society of Cardiology (ESC) has published guidelines for the investigation of patients with suspected heart failure and, if the diagnosis is proven, their subsequent management.
van Gilst, WH, Eastaugh, Joanne, Cohen-Solal, A., Gilst, W. H. van, Gavazzi, A, Freemantle, N, Cleland, JG, Gavazzi, A., Hobbs, Frederick, Moiseyev, VS, Dietz, R, van Gilst, W.H., Cleland, J.G., Hobbs, R, Korewicki, J., Follath, F., Hobbs, R., Mason, J., Eastaugh, J, Cohen-Solal, A, Préda, István, Cleland, JGF, Freemantle, Nick, Madeira, HC, Widimsky, J, Swedberg K Follath, F, Dietz, R., Cleland, J. G. F., Widimsky, J., Swedberg, K, Eastaugh, J., Preda, [No Value], Madeira, H. C., Moiseyev, V. S., Aguilar, JC, Aguilar, J.C., Komajda, M., Freemantle, N., Komajda, M, Preda, I., Korewicki, J, Aguilar, J. C., Mason, J, Madeira, H.C., Preda, I, Moiseyev, V.S., Swedberg, K., Follath, F   +47 more
core   +1 more source

Application of multidisciplinary collaboration-based rehabilitation exercise in the rehabilitation nursing of a patient with left ventricular assist device implantation (多学科协作模式下1例左心室辅助装置植入患者的康复运动护理体会)

中西医结合护理
This paper summarized the practice of a multidisciplinary collaboration-based rehabilitation exercise plan in the rehabilitation nursing of a patient with left ventricular assist device (LVAD) implantation.
WU Zhaofeng (吴兆风), ZHAO Ding (赵丁), SHI Li (史丽)   +2 more
doaj   +1 more source