Results 31 to 40 of about 2,074,138 (265)

Efficacy and safety of tyrosine kinase inhibitors in advanced hepatocellular carcinoma patients with Child-Pugh A and B cirrhosis: a meta-analysis

Frontiers in Pharmacology
BackgroundHepatocellular carcinoma (HCC) remains a leading cause of cancer mortality. Tyrosine kinase inhibitors (TKIs) are widely used in advanced HCC, yet outcomes may differ by hepatic reserve.
Xionglin Liu, Xionglin Liu, Jindu Li, Jindu Li, MinJun Li, MinJun Li, Bangde Xiang, Bangde Xiang   +7 more
doaj   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source

Genetic and molecular assessment of the relationship between smoking and EBV reactivation: A two-sample Mendelian randomization and in-vitro experimental study

Science Progress
Objective To assess whether modifiable lifestyle factors (particularly tobacco smoking) have a potential causal effect on Epstein–Barr virus (EBV) reactivation proxied by anti-EBV IgG seropositivity using Mendelian randomization (MR), and to explore the ...
Weiren Xiang, Nan Shi, Zhenqiu Luo, Fangfang Chen, Shi Luo, Yu Ren, Jingyu Li, Xiang Bin, Guangyao He, Xiang Yi, Wei Xia, Anzhou Tang   +11 more
doaj   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Bioinformatics and clinical analysis of CETN2’s impact on platinum resistance and prognosis in epithelial ovarian cancer

Journal of Ovarian Research
Objective To investigate the role of centrin-2 (CETN2) in platinum resistance and its underlying mechanisms in ovarian cancer. Methods We conducted a pan-cancer analysis of CETN2 expression and its associated genes using the STRING and TIMER databases ...
Lin-yuan Wei, Li Li
doaj   +1 more source

Risk of head and neck cancer in relation to blood inflammatory biomarkers in the Swedish AMORIS cohort

Frontiers in Immunology, 2023
BackgroundInflammation is critically involved in the development of human cancer, and blood inflammatory biomarkers have been proposed to indicate the risk of different cancer types.MethodsUsing the Swedish Apolipoprotein-Related Mortality Risk (AMORIS ...
Yanping Yang, Yanping Yang, Yanping Yang, Yushan Liang, Yushan Liang, Yushan Liang, Fatemeh Sadeghi, Maria Feychting, Niklas Hamar, Fang Fang, Zhe Zhang, Zhe Zhang, Zhe Zhang, Qianwei Liu   +13 more
doaj   +1 more source

Acute Neurological Events in Children With Hemoglobin SC Disease: A Multicenter Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurological manifestations in children with hemoglobin SC (HbSC) disease remain insufficiently characterized, particularly regarding acute events. The aim of this study was to describe the spectrum and frequency of acute neurological events in a multicenter cohort of children with HbSC disease.
Célia Paulmin, Bérengère Koehl, Audrey Maudoux, Hanine Mansour, Marie‐Hélène Odievre, Nathalie Garrec, Emilie Georget, Cécile Arnaud, Slimane Allali, Lydia Doumdo, Marie Belloy, Corinne Guitton   +11 more
wiley   +1 more source

Study on the mechanisms of raloxifene inhibiting oral squamous cell carcinoma cells

Guangxi Yike Daxue xuebao
Objective To explore the effect of raloxifene (RAL) on the malignant phenotypes of oral squamous cell carcinoma (OSCC) and its potential molecular mechanisms. Methods The target genes of RAL were predicted using TargetNet, SEA, and STITCH databases.
Quanxiang Hao, Qingbin Pan, Lixian Deng, Wanqi Wei, Xiaoying Zhou, Ping Li   +5 more
doaj   +1 more source

Used Daily Dose vs. Defined Daily Dose—Contrasting Two Different Methods to Measure Antibiotic Consumption at the Farm Level

Frontiers in Veterinary Science, 2019
Tackling the problem of rising antibiotic resistance requires valid and comparable data on the use of antimicrobial drugs in livestock. To date, no harmonized monitoring of antimicrobial usage in animals is available, and there is no system to assess ...
Svetlana Kasabova, Maria Hartmann, Nicole Werner, Annemarie Käsbohrer, Annemarie Käsbohrer, Lothar Kreienbrock   +5 more
doaj   +1 more source

Burden of liver cancer due to hepatitis C from 1990 to 2019 at the global, regional, and national levels

Frontiers in Oncology, 2023
BackgroundLiver cancer due to hepatitis C (LCDHC) is one of the leading causes of cancer-related deaths worldwide, and the burden of LCDHC is increasing. We aimed to report the burden of LCDHC at the global, regional, and national levels in 204 countries
Jie Wei, Jie Wei, Jie Wei, Guoqing Ouyang, Guoqing Ouyang, Guoqing Ouyang, Guozhen Huang, Guozhen Huang, Guozhen Huang, Yong Wang, Yong Wang, Yong Wang, Shuangjiang Li, Shuangjiang Li, Shuangjiang Li, Jiaping Liu, Jiaping Liu, Jiaping Liu, Yanhong Zhang, Guandou Yuan, Guandou Yuan, Guandou Yuan, Songqing He, Songqing He, Songqing He   +24 more
doaj   +1 more source